肝内胆管癌外科治疗的若干问题  

Several issues in the surgical treatment of intrahepatic cholangiocarcinoma

作　　者：司安锋 雷正清 程张军[2] SI Anfeng;LEI Zhengqing;CHENG Zhangjun(Department of General Surgery,General Hospital of Eastern Theater Command,Nanjing 210002,China;Hepatobiliary and Pancreatic Center,Zhongda Hospital Affiliated to Southeast University,Nanjing 210009,China)

机构地区：[1]东部战区总医院普通外科,南京210002 [2]东南大学附属中大医院肝胆胰中心,南京210009

出　　处：《临床肝胆病杂志》2024年第12期2351-2357,共7页Journal of Clinical Hepatology

基　　金：国家自然科学基金面上项目(81871988);国家自然科学基金青年科学基金项目(82103009)。

摘　　要：肝内胆管癌(ICC)在肝脏恶性肿瘤中发病率居第二位,恶性程度高、预后差。手术治疗目前仍是ICC可能获得治愈的唯一手段,但其R0切除率相对较低、术后无复发生存时间短。合理的切缘宽度、解剖性肝切除的价值、淋巴结清扫的地位以及腹腔镜肝切除和肝移植的肿瘤学效果等诸多问题仍有待厘清。本文旨在讨论ICC外科治疗策略的相关研究进展和存在的争议,以期为临床治疗决策提供参考。Intrahepatic cholangiocarcinoma(ICC)ranks second among malignant liver tumors and has high malignancy and poor prognosis.Currently,surgical treatment remains the only potentially curative therapy for ICC,but with a relatively low R0 resection rate and a short recurrence-free survival time after surgery.There are still several issues that need to be clarified,such as reasonable margin width,the value of anatomical hepatectomy,the role of lymph node dissection,and the oncological efficacy of laparoscopic liver resection and liver transplantation.This article reviews the research advances in surgical treatment strategies for ICC and related controversies,in order to provide a reference for clinical decision-making.

关 键 词：胆管上皮癌 外科手术 治疗学 

分 类 号：R735.7[医药卫生—肿瘤]