基于共价有机骨架的水凝胶固相萃取在农药检测中的应用  

Solid Phase Extraction Based on Covalent Organic Framework Hydrogel and Its Application in Pesticide Detection

作　　者：孙蕾 刘凌志 刘玉碟 沈晓芳[2] SUN Lei;LIU Ling-zhi;LIU Yu-die;SHEN Xiao-fang(Xinjiang Uygur Autonomous Region Product Quality Supervision and Inspection Institute,Urumqi 830011,China;School of Food Science and Technology,Jiangnan University,Wuxi 214122,China)

机构地区：[1]新疆维吾尔自治区产品质量监督检验研究院,新疆乌鲁木齐830011 [2]江南大学食品学院,江苏无锡214122

出　　处：《分析测试学报》2025年第1期145-154,共10页Journal of Instrumental Analysis

基　　金：新疆维吾尔自治区智力援疆创新拓展人才计划(小组团援疆团队计划)。

摘　　要：食品中农药残留超标对生物多样性以及人类健康造成潜在威胁。固相萃取技术广泛应用于农药的萃取,该方法的核心是吸附材料的选择。共价有机骨架(COFs)材料因其独特的优点在样品预处理中得到广泛的关注,而COFs的结构决定了材料的吸附性能,这对提高农药的萃取效果有重要作用。该研究制备了6种不同结构与性质的COFs(同一母体接枝不同官能团、具有不同带电性质、具有不同共轭结构),在不改变COFs结构的情况下,将其制备为COFs-海藻酸钠水凝胶(CACPs),建立了CACPs-分散固相萃取(CACPs-dSPE)方法,比较不同CACPs对氨基甲酸酯类、三唑类以及三嗪类农药的萃取效果。利用扫描电子显微镜、傅里叶变换红外光谱、X射线晶体衍射等方法对系列COFs以及系列CACPs的形貌、结构与性质进行表征。CACPs-dSPE结合高效液相色谱(HPLC)或紫外-可见分光光度法(UV-Vis)探究萃取效果,并结合理论计算模拟COFs与待测物的结合情况,探讨了不同CACPs对氨基甲酸酯类、三唑类以及三嗪类农药的吸附机理。结果表明:CACPs对不同类型农药的吸附性能是由其多孔结构性质(比表面积、孔径大小)和所负载COFs的固有结构协调决定,大的共轭结构、接枝羟基基团的COFs所制备的CACPs最有利吸附三类农药,其中Dt-TAPB-CACPs的萃取效果最佳。这为萃取农药过程中吸附材料的选择和设计提供了理论指导。Excessive pesticide residues in food pose a potential threat to biodiversity and human health.Solid phase extraction(SPE)technology is widely used in the extraction of pesticides,and the core of this method is the selection of adsorbent materials.Covalent organic frameworks(COFs)have attracted significant attention in sample pretreatment due to their unique advantages.The struc⁃ture of COFs determines the material's adsorption performance,which plays a crucial role in improv⁃ing pesticide extraction efficiency.In this study,six COFs with different structural properties(grafting different functional groups onto the same parent material,possessing different charged properties and conjugated structures)were prepared.To facilitate experimentation without altering the structure of the COFs,they were formulated into COFs-sodium alginate hydrogels(CACPs).A CACPs-dispersed solid-phase extraction(CACPs-dSPE)method was established to compare the ex⁃traction effects of different CACPs for carbamate,triazole,and triazine pesticides.Scanning elec⁃tron microscopy,Fourier transform infrared spectroscopy,X-ray crystal diffraction and other meth⁃ods were used to characterise the morphology,structures and properties of the series of COFs as well as the series of CACPs.The extraction effect was investigated by CACPs-dSPE combined with high performance liquid chromatography(HPLC)or ultraviolet-visible spectrophotometry(UV-Vis).By combining theoretical calculations to simulate the binding of COFs with the analyte,this study explores the adsorption mechanism of different CACPs on carbamate,triazole,and triazine pesti⁃cides.The results showed that the optimal adsorption performance of CACPs for different types of pes⁃ticides varied,which was coordinately determined by the nature of their porous structure(specific sur⁃face area,pore size)and the intrinsic structure of the loaded COFs(size of conjugated structure,grafted groups).The CACPs prepared by COFs with large conjugated structures and grafted hydroxyl groups were m

关 键 词：农药残留 共价有机骨架 COFs-海藻酸钠水凝胶 分散固相萃取(dSPE) 吸附机理 

分 类 号：O657.72[理学—分析化学] F767.2[理学—化学]