差异化能量激光调控正畸牙移动相关动物实验的研究进展  

Research progress on animal experiments of differential energy laser regulation of orthodontic tooth movement

作　　者：张可 赵颖[1] Zhang Ke;Zhao Ying(Xuanwu Hospital Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院口腔科,北京100053

出　　处：《中华口腔正畸学杂志》2024年第4期218-222,共5页Chinese Journal of Orthodontics

摘　　要：正畸治疗周期普遍较长,患者难于接受的同时也增加罹患其他口腔疾病的风险。近期在多种加速正畸牙移动方法的研究报道中,低能量激光加速正畸牙移动备受人们关注,从有限的研究中发现能量密度较高的激光不仅不能加速正畸牙移动,还可能产生抑制正畸牙移动的效果,其原因在于差异化能量密度的激光对组织产生了双向作用。利用高能量密度激光抑制正畸牙移动作为无创增强支抗的新方法,可能成为一个新的探索方向,相关机制需要进一步深入研究。本文针对差异化能量密度激光调控正畸牙移动的相关动物实验研究,从动物模型建立、激光调控正畸牙移动效果、牙周组织学变化以及骨改建相关基因和蛋白表达,到加速与抑制正畸牙移动的适宜激光参数选择等方面进行系统综述,为动物实验和临床研究提供参考。Orthodontic treatment cycles are generally long,which is difficult for patients to accept and also increases the risk of other oral diseases.Recently,among various methods for accelerating orthodontic tooth movement,low-energy laser acceleration has attracted considerable attention.From the limited research available,we find that higher energy density lasers not only fail to accelerate orthodontic tooth movement but may also inhibit it.The reason lies in the bidirectional effect that different energy density lasers have on tissues.Using high-energy density lasers to inhibit orthodontic tooth movement as a non-invasive method for enhancing anchorage could become a new exploration direction,though the underlying mechanisms require further in-depth study.This paper systematically reviews animal experimental studies on the regulation of orthodontic tooth movement by differential energy density lasers,covering aspects such as the establishment of animal models,the effects of laser regulation on tooth movement,periodontal tissue histological changes,bone remodeling-related gene and protein expression,and the selection of appropriate laser parameters for accelerating or inhibiting tooth movement.The aim of this review is to provide a reference for animal experiments and clinical research.

关 键 词：低能量激光 加速正畸牙移动 高能量激光 抑制正畸牙移动 动物实验 

分 类 号：R783.5[医药卫生—口腔医学]