基于扩展现实的眼镜式可穿戴视觉训练系统在黄斑裂孔术后患者康复中的应用  

Application of wearable visual training system based on extended reality glasses in patients after macular hole surgery

作　　者：袁静[1] 王兴昌 孙锡全 焦辉广 王倩 俞建雄[3] 涂碧玥 严茜茜[1] 赵振 童艳霞 张书文 Yuan Jing;Wang Xingchang;Sun Xiquan;Jiao Huiguang;Wang Qian;Yu Jianxiong;Tu Biyue;Yan Xixi;Zhao Zhen;Tong Yanxia;Zhang Shuwen(Eye Center,Renmin Hospital of Wuhan University,Wuhan 430060,China;Shenzhen Vison Stick Medical Technology Co.,Ltd.,Shenzhen 518055,China;Department of Gastrointestinal Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院眼科中心,武汉430060 [2]深圳视力棒医疗科技有限公司,深圳518055 [3]武汉大学人民医院胃肠外科,武汉430060

出　　处：《中华实验眼科杂志》2024年第12期1142-1147,共6页Chinese Journal Of Experimental Ophthalmology

基　　金：湖北省重点研发计划(2021BCA125)。

摘　　要：目的评价基于扩展现实(XR)的眼镜式可穿戴视觉训练设备短期使用对黄斑裂孔术后患者的康复效果。方法采用自身对照研究方法,于2022年10月至2024年3月在武汉大学人民医院眼科中心连续招募黄斑裂孔术后单眼低视力患者11例11眼作为研究对象。所有患者采用自主研发的视觉康复训练镜LOOKBON T10进行生物反馈训练3个月,比较训练前后LogMAR最佳矫正视力(BCVA)、视网膜敏感度、有效注视率、固视稳定性、阅读速度、视物垂直变形度(MV)和水平变形度(MH)及视觉相关生活质量评分量表(CVRQoL-25)评分。结果患者训练后BCVA、视网膜敏感度、有效注视率、固视稳定率、阅读速度分别为0.69±0.19、(21.61±2.75)db、(92.43±4.06)%、(93.09±4.31)%和(104.82±21.85)个/min,较训练前的0.85±0.28、(17.71±3.17)db、(31.83±19.05)%、(32.35±19.12)%和(69.64±20.17)个/min明显改善,差异均有统计学意义(t=5.253、-5.987、-11.561、-12.003、-11.682,均P<0.001)。训练后MV和MH分别为(0.29±0.20)°和(0.21±0.24)°,较训练前的(0.44±0.24)°和(0.43±0.41)°明显减轻,差异均有统计学意义(t=9.238、4.068,均P<0.01)。训练后CVRQoL-25评分为(1193.18±229.43)分,较训练前的(947.73±203.86)分显著提高,差异有统计学意义(t=-11.687,P<0.001)。结论基于XR的眼镜式可穿戴视觉训练设备能有效改善黄斑裂孔术后视功能恢复不佳患者的视功能,提高患者生活质量。Objective To evaluate the short-term rehabilitation effect of wearable visual training devices based on extended reality(XR)glasses in patients after macular hole surgery.Methods A self-controlled study was conducted.Eleven patients with monocular low vision after macular hole surgery were recruited at Renmin Hospital of Wuhan University from October 2022 to March 2024.All patients underwent biofeedback training for 3 months using the independently developed visual rehabilitation training glasses LOOKBON T10.The LogMAR best corrected visual acuity(BCVA),retinal sensitivity,effective fixation rate,fixation stability,reading speed,vertical metamorphopsia(MV),horizontal metamorphopsia(MH),and Chinese version of the visual-related quality of life assessment form(CVRQoL-25)were compared before and after training.This study adhered to the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Renmin Hospital of Wuhan University(No.WDRY2024-K263).Written informed consent was obtained from each subject.Results After training,the patients'BCVA,retinal sensitivity,effective fixation rate,fixation stability,and reading speed were 0.69±0.19,(21.61±2.75)db,(92.43±4.06)%,(93.09±4.31)%,and(104.82±21.85)characters/minute,respectively,which were significantly improved compared to 0.85±0.28,(17.71±3.17)db,(31.83±19.05)%,(32.35±19.12)%,and(69.64±20.17)characters/minute before training(t=5.253,-5.987,-11.561,-12.003,-11.682;all at P<0.001).After training,MV and MH were(0.29±0.20)°and(0.21±0.24)°,respectively,which were significantly reduced compared to pre-training(0.44±0.24)°and(0.43±0.41)°(t=9.238,4.068;both at P<0.01).After training,the CVRQoL-25 score was 1193.18±229.43,which was significantly higher than pre-training 947.73±203.86(t=-11.687,P<0.001).Conclusions The application of wearable visual training equipment based on XR glasses can effectively improve the visual function of patients with poor visual function recovery after macular hole surgery,and enhance their quality of li

关 键 词：低视力 可穿戴电子设备 黄斑裂孔 生物反馈训练 低视力康复 扩展现实 优选视网膜位点 受训视网膜位点 

分 类 号：R779.6[医药卫生—眼科]