Exploration of peripheral blood ZSCAN12 mRNA expres-sion levels in patients with first-episode schizophrenia  

作　　者：Ran Tian Chen Yu Xudong Zhou Zhilan Yang 

机构地区：[1]Department of Clinical Psychology,The Affiliated Mental Hospital of Kunming Medical University,Kunming 650000,China

出　　处：《Journal of Translational Neuroscience》2024年第4期47-51,共5页转化神经科学电子杂志（英文）

基　　金：supported by Research Project of Yunnan Provincial Psychiatric Hospital(SJKY-2023-08).

摘　　要：Objective:To investigate the changes of mRNA expression level of zinc finger and SCAN domain containing 12(ZSCAN12)in peripheral blood of first-ep-isode schizophrenia(SCZ).Methods:For our study we selected 17 individuals who had a first episode of SCZ and were hospitalized in the Affiliated Mental Hospital of Kunming Medical University from January 2024 to June 2024;we measured the mRNA expression level of ZSCAN12 in peripheral lymphocytes by quantitative re-al-time polymerase chain reaction(Q-PCR)method in the study group and compared it to a control group consisting of 15 healthy patients.Results:There was no significant difference in the expression of ZSCAN12 mRNA in pe-ripheral blood lymphocytes of SCZ patients and healthy controls(P>0.05).Conclusion:The expression of ZS-CAN12 mRNA was not significantly abnormal in SCZ patients in this study.

关 键 词：SCHIZOPHRENIA zinc finger and SCAN domain containing 12 peripheral lymphocytes 

分 类 号：R749.3[医药卫生—神经病学与精神病学]