羧甲基壳聚糖银正畸黏结剂体外远期抗菌效果及着色情况的研究  

Long-term Antimicrobial Activity in Vitro and Coloring Situation of Experimental Silver Carboxymethyl Chitosan—Containing Orthodontic Cements

作　　者：门靖旋 MEN Jingxuan(Huizhou Stomatological Hospital,Huizou 516000,China)

机构地区：[1]惠州口腔医院,广东惠州516000

出　　处：《工业微生物》2024年第6期16-18,共3页Industrial Microbiology

基　　金：惠州市市级科技计划项目“羧甲基壳聚糖银正畸黏结剂抗菌性及机械性能的研究”(编号:2022CZ010279)。

摘　　要：文章观察羧甲基壳聚糖银(CMCT-Ag^(+))正畸黏结剂的体外远期抗菌效果及牙面着色情况,以变形链球菌为评价菌种,将CMCT-Ag^(+)以1.5%的质量比添加到3M光固化正畸黏结剂中,模拟口腔环境,并在四个月后,检测远期抗菌效果,同时将该黏接剂在离体牙上黏结托槽,并将其置于人工唾液中浸泡四个月,检测牙面着色情况。研究发现添加质量比为1.5%的羧甲基壳聚糖银-正畸黏结剂,四个月后的远期抗菌效果较为理想,六个月后牙面未见明显着色;添加CMCT-Ag^(+)的3M光固化正畸黏结剂对变形链球菌有明显的远期抑制作用,能够满足正畸的临床需求,且未出现牙齿着色问题。The long-term antimicrobial activity in vitro and tooth surface coloring situation of experimental silver carboxymethyl chitosan(CMCT-Ag^(+))—containing orthodontic cements are observed.The streptococcus mutans is an experimental bacterium.The silver carboxymethyl chitosan at a mass ratio of 1.5%is added to 3M UV curable orthodontic adhesive to simulate the oral environment for 4 months to observe its long-term antimicrobial activity.This adhesive was used to bond brackets to detached teeth,and they were soaked in artificial saliva for four months to detect the coloring situation of the tooth surface.The containing orthodontic cements added the mass ratio of 1.5%silver carboxymethyl chitosan has good long-term antibacterial activity after four months,and there was no significant dentistry stained after six months.The CMCT-Ag^(+)—containing orthodontic cements has a good long-term antibacterial property on Streptococcus mutans and can satisfy the clinical need of dental orthopaedics,without the tooth coloring problems.

关 键 词：羧甲基壳聚糖银 变形链球菌 远期抗菌性 

分 类 号：R783.1[医药卫生—口腔医学]