缝合止血与电凝止血对腹腔镜卵巢囊肿剔除术患者卵巢储备功能的影响  

Effects of Suture and Electrocoagulation Hemostasis in Laparoscopic Ovarian Cyst Removal Patients for Ovarian Reserve Function

作　　者：宋利 李瑞玲 吴艳红 SONG Li;LI Ruiling;WU Yanhong(Department of Obstetrics and Gynecology,Liling Tai’an Hospital,Liling 412200,China;不详)

机构地区：[1]醴陵泰安医院妇产科,湖南醴陵412200

出　　处：《中国医学创新》2025年第1期60-64,共5页Medical Innovation of China

摘　　要：目的:比较缝合止血与电凝止血对腹腔镜卵巢囊肿剔除术(LOCR)患者卵巢储备功能的影响。方法:选取2020年10月—2023年10月于醴陵泰安医院行LOCR治疗的患者共计124例,以随机数字表法分成电凝组(n=62)和缝合组(n=62),缝合组给予缝合止血,电凝组给予电凝止血,比较两组围手术期指标、卵巢储备功能、免疫功能及术后并发症。结果:电凝组手术时间较缝合组短,术后首次排气时间、首次下床时间均较缝合组早,术中出血量较缝合组少,差异均有统计学意义(P<0.05);两组术后1个月黄体生成素(LH)、卵泡刺激素(FSH)水平均升高,抑制素B(INHB)、抗苗勒管激素(AMH)水平均下降,但缝合组LH、FSH水平均较电凝组低,INHB、AMH水平均高,差异均有统计学意义(P<0.05);两组术后1个月CD3^(+)、CD4^(+)均下降,CD8^(+)均升高,但缝合组CD3^(+)、CD4^(+)均较电凝组高,CD8^(+)低,差异均有统计学意义(P<0.05);缝合组术后并发症发生率为3.23%(2/62),与电凝组的6.45%(4/62)比较差异无统计学意义(P>0.05)。结论:LOCR患者采用缝合止血与电凝止血均具有较高的安全性,但电凝止血术中出血量更少,手术时间更短,术后恢复更快,而缝合止血对卵巢储备功能及免疫功能的影响较小,临床需根据患者实际选择合适的止血方法,以提高手术效果。Objective:To compare the effect of suture and electrocoagulation hemostasis in laparoscopic ovarian cyst removal(LOCR)patients for ovarian reserve function.Method:A total of 124 patients from October 2020 to October 2023 who received LOCR treatment in Liling Tai’an Hospital were selected.They were divided into electrocoagulation group(n=62)and suture group(n=62)by random number table method.The suture group was given suture hemostasis,and the electrocoagulation group was given electrocoagulation hemostasis.The perioperative indicators,ovarian reserve function,immune function,and postoperative complications in both groups were compared.Result:The operation time in the electrocoagulation group was shorter than that in the suture group,the first postoperative exhaust time and the first time to get out of bed in the electrocoagulation group were earlier than those in the suture group,and the intraoperative blood loss was less than that in the suture group,the differences were statistically significant(P<0.05).Luteinizing hormone(LH)and follicle-stimulating hormone(FSH)levels were increased,and inhibin B(INHB)and anti-Muller tube hormone(AMH)levels were decreased in both groups one month after surgery,but the levels of LH and FSH in suture group were lower than those in electrocoagulation group,and INHB and AMH levels were higher,with statistical significance(P<0.05).One month after surgery,CD3^(+),CD4^(+)decreased and CD8^(+)increased in both groups,but the CD3^(+)and CD4^(+)in suture group were higher than those in electrocoagulation group,and CD8^(+)was lower,with statistical significance(P<0.05).The incidence of postoperative complications in the suture group was 3.23%(2/62),which had no statistical significance compared with 6.45%(4/62)in the electrocoagulation group(P>0.05).Conclusion:Both suture hemostasis and electrocoagulation hemostasis have high safety for patients undergoing LOCR.However,electrocoagulation hemostasis has shorter surgical time,less intraoperative bleeding,and faster postoperative recovery

关 键 词：缝合止血 电凝止血 腹腔镜卵巢囊肿剔除术 卵巢储备功能 

分 类 号：R737.31[医药卫生—肿瘤]