DCE-MRI直方图定量参数联合DWI在乳腺癌早期诊断中的应用价值  

The Value of DCE-MRI Histogram Quantitative Parameters Combined with DWI in the Early Diagnosis of Breast Cancer

作　　者：刘文霞 贡琦 刘利 吴丽萍 郑岚[1] 张茂红 LIU Wen-xia;GONG Qi;LIU Li;WU Li-ping;ZHENG Lan;ZHANG Mao-hong(Medical Imaging Department of Zaozhuang Maternal and Child Health Hospital,Zaozhuang 277100,Shandong Province,China)

机构地区：[1]枣庄市妇幼保健院医学影像科,山东枣庄277100

出　　处：《中国CT和MRI杂志》2025年第1期106-108,共3页Chinese Journal of CT and MRI

基　　金：山东省妇幼保健协会科技创新项目(20210210)。

摘　　要：目的探讨MRI动态增强扫描(DCE-MRI)直方图定量参数联合扩散加权成像(DWI)在乳腺癌早期诊断中的应用价值。方法回顾性收集2017年9月至2021年9月期间在本院进行手术治疗的120例女性乳腺病变患者,依据术后病理结果分为良性组(n=78)与恶性组(n=42),两组均在手术前进行DCEMRI及DWI检查,依据软件得出DCE-MRI直方图定量参数及ADC值,比较DCE-MRI直方图定量参数及ADC的组间差异,绘制ROC曲线,分析直方图定量参数与DWI联合用于早期诊断乳腺癌的价值。结果相较于良性组,恶性组的K^(trans)中位数、平均值、第90%位数,K_(ep)第90%位数、V_(p)中位数、平均值、第50%位数均高,ADC值低于良性组,差异有统计学意义(P<0.05);绘制ROC曲线图,结果显示,DCEMRI直方图定量参数联合DWI对乳腺癌早期诊断的AUC=0.969>0.7,诊断效能较好,最佳敏感度、特异度为90.50%、96.20%。结论DCE-MRI直方图定量参数联合DWI在乳腺癌早期诊断中具有较高的临床应用价值。Objective Analysis of the value of DCE-MRI histogram quantitative parameters combined with DWI in early diagnosis of breast cancer.Methods A retrospective collection was conducted on 120 female patients with breast lesions who underwent surgical treatment in our hospital from September 2017to September 2021.They were divided into a benign group(n=78)and a malignant group(n=42)based on postoperative pathological results.DCE-MRI and DWI were perfo rmed befo re surgery in both groups.The quantitative parameters of DCE-MRI histogram and ADC values were obtained according to the softwa re.The differences between the quantitative para meters of DCE-MRI histogra m and ADC between groups were compared,and the ROC was drawn to compare the quantitative parameters of DCE-MRI histogram and DWI in the early diagnosis of breast cancer.Results The median,mean,and 90th percentile K^(trans),K_(ep)90th percentile,V_(p) median,mean,and 50th percentile were higher in the malignant group than in the benign group,while the ADC value was lower in the benign group,with a statistical significant difference(P<0.05).Receiver operating characteristic was drawn,and the results showed that the AUC of DCE-MRI histogram quantitative parameters combined with DWI for early diagnosis of breast cancer was 0.969>0.7,and the diagnostic efficiency was good,with the best sensitivity and specificity of 90.50%and 96.20%.Conclusion The quantitative parameters of DCE-MRI histogra m combined with DWI have high clinical value in the ea rly diagnosis of breast cancer.

关 键 词：MRI动态增强扫描 直方图 扩散加权成像 乳腺癌 早期诊断 

分 类 号：R737.9[医药卫生—肿瘤]