胆固醇结晶与急性缺血性卒中1例报告  

Cholesterol crystals and acute ischemic stroke:A case report

作　　者：易茜云 蔡刚 李军 方旭明 张甲岩 陈红群 朱英武 成元华 楚兰 YI Qianyun;CAI Gang;LI Jun(Department of Neurology,The Affiliated Hospital of Guizhou Medical University,Guiyang 550004,China)

机构地区：[1]贵州医科大学附属医院神经内科,贵州贵阳550004 [2]贵州医科大学临床医学院,贵州贵阳550025 [3]贵州医科大学附属医院病理科,贵州贵阳550004

出　　处：《中风与神经疾病杂志》2024年第12期1134-1136,共3页Journal of Apoplexy and Nervous Diseases

基　　金：贵州省卫生健康委科学技术基金项目(gzwjkj2019-1-062)。

摘　　要：急性缺血性卒中(ALS)患者合并串联闭塞病因多为动脉粥样硬化,机制可能是动脉粥样硬化原位血栓形成,部分血栓或斑块脱落导致远端动脉栓塞。血栓或栓子中发现的动脉粥样硬化成分有助于闭塞病因的诊断及斑块评估。本文通过1例右侧前循环串联闭塞的急性缺血性卒中患者,在颈内动脉血管成形治疗时发生了栓子脱落,栓子病理学发现的大量胆固醇结晶为卒中病因分型及斑块评估提供了帮助。Atherosclerosis is the main etiology of tandem occlusion in patients with acute ischemic stroke,with the possible mechanisms of in situ thrombosis due to atherosclerosis or distal arterial embolization due to the dislodgment of partial thrombi or plaques.The atherosclerotic elements identified within the thrombus or emboli can help with the diagnosis of the etiology of occlusion and the evaluation of plaques.This article reports a case of acute ischemic stroke due to tandem occlusion of the right anterior circulation,and the dislodgment of thrombi occurred during internal carotid artery angioplasty.The pathological analysis of the thrombi revealed a large amount of cholesterol crystals,which helped with the etiological classification of stroke and the evaluation of plaques.

关 键 词：急性缺血性卒中 动脉粥样硬化 血栓 胆固醇结晶 

分 类 号：R743.3[医药卫生—神经病学与精神病学]