老年血液透析患者认知衰弱现状及其影响因素分析  

Analysis of cognitive weakness and influencing factors in elderly hemodialysis patients

作　　者：姚迟 杨晓娟[1] YAO Chi;YANG Xiao-juan(The Second People's Hospital of Hefei,Hefei 230000,Anhui)

机构地区：[1]合肥市第二人民医院肾内科,安徽合肥230000

出　　处：《安徽医专学报》2024年第6期126-128,共3页Journal of Anhui Medical College

基　　金：2021年度安徽医科大学校科研基金项目(编号:2012xkj153)。

摘　　要：目的:探讨老年血液透析患者认知衰弱现状及影响因素。方法:将医院收治的50例老年血液透析患者纳为研究对象,根据患者有无认知衰弱将其分为认知正常组(30例,MMSE<27分)认知衰弱组(20例,MMSE≥27分),对两组患者进行问卷调查分析,并应用Logistic回归分析认知衰弱的影响因素。结果:认知正常组患者红细胞、血红蛋白、血小板、肌酐、总胆固醇、总蛋白、白蛋白、性别构成比与认知衰弱组比较,差异均无统计学意义(P>0.05),认知正常组患者年龄、血磷、白细胞、淋巴细胞、尿素氮、尿酸、甘油三酯、超敏C反应蛋白、CFAI评分、透析时间显著低于认知衰弱组(P<0.05),认知正常组患者血钙水平显著高于认知衰弱组(P<0.05)。结论:年龄、血磷、白细胞、淋巴细胞、尿素氮、尿酸、甘油三酯、超敏C反应蛋白、血钙、透析时间、CFAI评分等因素都是老年血液透析患者认知衰弱的影响因素。Objective:To analyze the status quo and influencing factors of cognitive frailty in elderly hemodialysis patients.Methods:Fifty elderly hemodialysis patients in hospital were included in the study.According to whether the patients had cognitive frailty,they were divided into cognitive normal group(30 cases,MMSE<27 points)and cognitive frailty group(20 cases,MMSE≥27 points).A questionnaire survey was conducted on the two groups of patients.The influencing factors of cognitive frailty were analyzed by Logistic regression.Result:There was no statistically significant difference in the gender composition ratio of red blood cells,hemoglobin,platelets,creatinine,total cholesterol,total protein,and albumin between the cognitively normal group and the cognitively impaired group(P>0.05).The age,blood phosphorus,white blood cells,lymphocytes,urea nitrogen,uric acid,triglycerides,high-sensitivity C-reactive protein,CFAI score,and dialysis time of the cognitively normal group were significantly lower than those of the cognitively impaired group(P<0.05),while the blood calcium of the cognitively normal group was significantly higher than that of the cognitively impaired group(P<0.05).Conclusion:Age,blood phosphorus,white blood cells,lymphocytes,urea nitrogen,uric acid,albumin,triglycerides,high-sensitivity C-reactive protein,blood calcium,dialysis time,CFAI score and other factors are all influencing factors of cognitive decline in elderly hemodialysis patients.

关 键 词：血液透析 认知衰弱 影响因素 

分 类 号：R749.1[医药卫生—神经病学与精神病学]