肝炎后肝硬化食管动力的变化  

Change of esophageal motility in cirrhotic patients with hepatitis virus

作　　者：徐章[1] 王一平[2] 吴俊超[2] 杨丽[2] 赵颖[2] 

机构地区：[1]郧阳医学院东风临床学院消化内科,湖北十堰442008 [2]华西医科大学附属第一医院消化内科,四川成都610041

出　　处：《临床肝胆病杂志》2002年第6期359-360,362,共3页Journal of Clinical Hepatology

摘　　要：探讨肝炎后肝硬化食管动力的变化。 4 0例肝炎后肝硬化 (非食管静脉曲张和轻、中、重度静脉曲张各 10例 )患者和 2 0名健康自愿者行食管测压检查。下食管括约肌静息压在各组间均无差异 (P值均 >0 0 5 )。食管体部远端蠕动波幅 (PA)、时间 (PD)差异有显著性 (P值均 <0 0 5 ) ,其中EV组和中、重度EV组较NC组PA显著降低、PD明显延长 (P <0 0 5～ <0 0 1)。食管体部近、远端蠕动传导速度 (PV)差异有显著性 (P <0 0 5～ <0 0 1)。在食管近端 ,EV组较NC组和NEV组明显减慢 (P <0 0 1～ <0 0 5 ) ,而在远端 ,EV组较NC组 ,重度EV组较轻、中度EV组PV也显著减慢 (P <0 0 5～ <0 0 1)。肝炎后肝硬化 (尤其是中、重度静脉曲张 )患者的食管动力变化主要是食管体部运动功能的异常 。To investigate the change of esophageal motility in cirrhotic patients with hepatitis virus. Esophageal menometry was performed in 40 cirrhotic patients (included 10 cases with non-esophageal varices, with small, middle and large esophageal varices respectively) with hepatitis virus and in 20 health volunteers. The mean resting pressure in lower esophageal sphincter was found no difference among the 3 groups and the 5 groups above. The perisaltic amplitude (PA) and duration (PD) of primary peristaltic wave in distal esophagus showed significant difference among above groups ( P <0 05). Cirrhosis groups with EV, middle and large EA revealed obvious decrease of PA and increase of PD compared with NC group ( P <0 05～<0 01).The peristaltic velocity (PV) of primary peristaltic waves in proximal and distal esophagus showed significant difference among 3 groups and 5 groups ( P <0 01～<0 05). These findings suggest that the changes of esophageal motality were dysfunction of the esophageal body and this might due to the mechanical effect of the presence of varicese.

关 键 词：肝炎后肝硬化 食管测压 食管动力 

分 类 号：R575.2[医药卫生—消化系统]