^(18)F-脱氧葡萄糖PET判断头颈部癌复发的价值  

^(18)F-deoxyglucose-PET in the detection of recurrence in head and neck cancer

作　　者：陈应瑞[1] 李伟雄[1] 辜梅新[1] 谢松喜[1] 

机构地区：[1]广东省人民医院放射治疗科,广州510080

出　　处：《中华放射肿瘤学杂志》2002年第4期217-219,共3页Chinese Journal of Radiation Oncology

摘　　要：目的　探讨1 8F 脱氧葡萄糖 (FDG)正电子发射型体层摄影术 (PET)在头颈部癌瘤复发的临床价值。方法　 37例头颈部恶性肿瘤 ,临床疑复发行FDGPET显像 (1 9例全身显像 ,1 8例局部显像 ) ,其中 34例同期行CT或MRI检查 ,最后诊断依靠病理检查和临床随访。结果　 37例患者中FDGPET显像阳性 2 5例 ,其中 3例假阳性 ;阴性 1 2例 ,其中假阴性 2例。FDGPET显像的敏感性、特异性和准确率分别为 91 .7%、76 .9%和 86 .5 % ,CT或MRI检查的分别为 68.2 %、75 .0 %和 61 .8%。在 1 9例FDGPET全身显像中 ,1 1例除头颈FDG异常浓聚外 ,6例还发现有远地转移。结论　评价头颈部癌瘤复发 ,FDGPET比CT或MRI有更高准确性。Objective To evaluate 18 F deoxyglucose positron emission tomography (FDG PET) in the detection of suspicious recurrence in head and neck cancers , as compared with CT/MRI imaging. Methods Thirty seven patients with clinically suspicious recurrences in head and neck cancers underwent FDG PET, with 34 checked with CT/MRI imaging. The final diagnosis of recurrence were proved by pathology or clinical following up. Results FDG PET detected recurrence successfully in 32 of 37(86.5%) patients with 3 false positives and 2 false negatives. The FDG PET sensitivity, specificity and accuracy in defining local recurrence were 91.7%, 76.9%, 86.5%, respectively; and those of CT/MRI were 68.2%, 75.0%, 61.8%, respectively. Conclusion In comparison with CT/MRI, FDG PET possesses a higher accuracy in detecting recurrence in head and neck cancers.

关 键 词：^18F-脱氧葡萄糖 PET 头颈部癌 复发 

分 类 号：R739.91[医药卫生—肿瘤]