趋势导向视野检查法与常规阈值视野检查法的对比研究  

The comparison between tendency-oriented perimetry and traditional threshold perimetry

作　　者：钟一声[1] 叶纹[1] 高骏[1] 俞方知[1] 王康孙[1] 

机构地区：[1]上海第二医科大学附属瑞金医院眼科,200025

出　　处：《中华眼底病杂志》2002年第4期269-272,共4页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的　评价趋势导向视野检查法 (tendency- oriented perimetry,TOP)在青光眼视功能检测中的应用价值。　方法　利用 Octopus10 1全自动视野计分别对 2 0名正常人的 2 0只正常眼、32例原发性开角型青光眼 (primary open- angle glaucoma,POAG)患者的 32只患眼和 14例可疑 POAG患者的 14只眼分别进行常规阈值视野检查 (Normal/Normal程序 )和 TOP视野检查 (TOP/Normal程序 )。所有受检眼在 2周内再次分别进行常规阈值视野检查和 TOP视野检查。将两种视野检查的结果、视野检查指数、点对点阈值变异及视野缺损点数进行比较和分析。　结果　TOP视野检查正常人的阴性检出率为 90 % ,POAG的阳性检出率为 75 % ,其中检测中晚期 POAG的阳性检出率达 10 0 %。 2种视野检查的视野指数呈明显正相关 ,平均敏感度 (mean sensitivity,MS)的相关系数为 0 .9335 ,平均缺损 (mean defect,MD)的相关系数为 0 .9189,偏离缺失 (loss variance,L V)的相关系数为 0 .96 2 1。点对点阈值变异和视野缺损点数 TOP视野检查结果略高于常规阈值视野检查结果 ,但二者间差异均无显著性的意义 (P=0 .2 0 19,P=0 .44 48)。　结论　TOP视野检查指数与常规阈值视野检查指数呈明显正相关 ,其检测中晚期 POAG的敏感性及可重复性高。Objective To evaluate the application of tendency-oriented perimetry (TOP) in detecting the visual function of glaucoma. Methods The traditional threshold perimetry (Normal/Normal strategy) and TOP (TOP/Normal strategy) carried out by Octopus 101 perimetry were used to examine the visual field of 20 normal subjects (20 eyes), 32 cases (32 eyes) of primary open-angle glaucoma (POAG), and 14 cases (14 eyes) of suspected POAG, respectively. The visual field outcomes, indices, point by point threshold variability and defective points of the two perimetries were compared and analysed. Results The negative rate of TOP was 90% in normal subjects. The positive rate of TOP was 75% in POAG , and 100% in middle and late stage of POAG. The visual field indices of two perimetries were positively correlated, with mean sensitivity (MS) of r=0.9335, mean defect (MD) of r=0.9189, and loss variance (LV) of r=0.9621. The point by point threshold variability and defective points of TOP were higher than those of traditional threshold perimetry, but the difference between the two perimetries was not significant (P=0.2019, P=0.4448). Conclusion The visual field indices of TOP and traditional threshold perimetry are positively correlated. The sensitivity and reproducibility of TOP are high in detecting the visual function of middle and late stage of POAG.

关 键 词：趋势导向视野检查法 视野检查法 阈限值 TOP 青光眼 

分 类 号：R770.42[医药卫生—眼科]