恶性肿瘤合并肺栓塞35例临床分析  

Clinical analysis on 35 cases of malignant tumor with pulmonary embolism

作　　者：刘歆 符翠萍[2,3] 励雯静[2,3] 吴晓丹 吴旭[2,3] 张舒琪 李善群[2,3] 

机构地区：[1]福建省老年医院呼吸科,福州350000 [2]复旦大学附属中山医院呼吸科,上海200032 [3]复旦大学呼吸病研究所,上海200032

出　　处：《世界临床药物》2015年第6期394-399,共6页World Clinical Drug

基　　金：上海市重点学科建设项目(B115);上海市科委国际合作课题(13430720500)

摘　　要：目的分析恶性肿瘤合并肺栓塞(PE)的一般临床特征、危险因素、实验室检查、诊断、治疗及预后。方法回顾性分析2009-2013年复旦大学附属中山医院收治入院恶性肿瘤合并PE的35例患者的临床资料,并收集同期不伴有恶性肿瘤的34例PE患者的临床资料作为对照,分析恶性肿瘤合并PE患者与单纯PE患者临床情况的异同点。结果恶性肿瘤合并PE组肺栓塞严重程度指数(PESI)评分高于对照组,疗效差于对照组,差异有统计学意义(P<0.05)。结论恶性肿瘤合并PE治疗效果差,临床需高度重视,建议采用低分子肝素抗凝并权衡出血风险考虑延长抗凝时间。Objective To discuss the general clinical features, risk factors, laboratory findings, diagnosis, treatment and prognosis of malignant tumor complicated with pulmonary embolism(PE). Methods In Zhongshan hospital from January 2009 to December 2013, 35 cases diagnosed as malignant tumors with PE as a case group were retrospectively reviewed, and 34 cases of PE not associated with malignant tumors in the same period were selected as control group. Results Pulmonary embolism severity index(PESI) of the case group was higher than that of the control group. Curative effect of the case group was poorer than the control group. Results indicated the significant difference between the case group and control group(P< 0.05). Conclusion PE is one of the major complication and leading causes of death in patients with malignant tumors. Extending anticoagulant therapy helps to improve the prognosis in cancer patients with PE.

关 键 词：恶性肿瘤 肺栓塞(PE) 危险因素 疗效 

分 类 号：R73[医药卫生—肿瘤] R563.5[医药卫生—临床医学]