结直肠癌的营养干预研究  

Nutritional Intervention Research of Colorectal Cancer

作　　者：付嵘[1] 李航[1] 陈若雷[1] 杨进[1] 董靖[1] 

机构地区：[1]西北大学生命科学学院,西安710069

出　　处：《基因组学与应用生物学》2015年第5期1076-1079,共4页Genomics and Applied Biology

基　　金：国家自然科学基金委基地能力提高项目(J1210063);陕西省教育厅2013年科学研究项目计划项目(JH13371);中国博士后科学基金第52批面上资助(BSH12012)共同资助

摘　　要：作为一种常见的消化道恶性肿瘤,结直肠癌(CRC)的发病率和死亡率逐年上升。营养不只是影响它的最危险因素之一,也是预防CRC的突破口。近年来,随着营养与结直肠癌临床关系研究的不断深入,营养干预和预防在结直肠癌临床领域逐渐得到了广泛的应用。本文在文献综述的基础上,探索了不同营养支持途径对增强CRC患者的免疫力和提高其治疗效果等方面的作用机理,并指出运用营养基因组学理论和方法开展CRC营养支持治疗研究具有广阔前景。Colorectal cancer is one of the most common gastrointestinal cancers, and its incidence and mortality are increasing year by year. As for CRC, the nutrition not only acts as a crucial invloving factor, but also plays an important role in CRC prevention. As the study on the link between nutrition and CRC has long been going deeply over the past years, the prevention and intervention of CRC from the stand-point of nutrition is being adopted widely. Based on literature explorations, this paper discusses the mechanisms of nutritional support that enhances the immunity and increases the efficacy of CRC cure, and the prospect of using theories and approches in nutrigenomics in the treatment of CRC.

关 键 词：结直肠癌 营养支持 基因组学 干预 

分 类 号：R735.34[医药卫生—肿瘤]