Vitreous substitutes: challenges and directions  

作　　者：Qian-Ying Gao Yue Fu Yan-Nian Hui 

机构地区：[1]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University [2]Department of Ophthalmology, Xijing Hospital, the Fourth Military Medical University

出　　处：《International Journal of Ophthalmology(English edition)》2015年第3期437-440,共4页国际眼科杂志（英文版）

基　　金：Supported by the "Twelfth Five-Year" Plan for Science & Technology Support Grant (No. 2012BAI08B02);the National 863 Project (No. 2009AA02Z404);the Guangdong Provincial Industry University Research Cooperation Plan (No. 2010A090200074)

摘　　要：The natural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels, particularly the former two vitreous substitutes are clinically widely used with certain complications. Those, however, are not real artificial vitreous due to lack of structure and function like the natural vitreous body. This article reviews the situations, challenges, and future directions in the development of vitreous substitutes, particularly the experimental and clinical use of a new artificial foldable capsular vitreous body.The natural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels, particularly the former two vitreous substitutes are clinically widely used with certain complications. Those, however, are not real artificial vitreous due to lack of structure and function like the natural vitreous body. This article reviews the situations, challenges, and future directions in the development of vitreous substitutes, particularly the experimental and clinical use of a new artificial foldable capsular vitreous body.

关 键 词：vitreous substitute artificial vitreous foldable capsular vitreous body silicone oil 

分 类 号：R776[医药卫生—眼科]