躁狂症患者外周血T淋巴细胞研究  

Study on T-cell subpopulation and related factors in manic patients

作　　者：朱金富[1] 贾福军[2] 许明智[2] 师天元[2] 张红亚[2] 

机构地区：[1]中南大学湘雅二医院精神卫生研究所,长沙410011 [2]河南省精神病医院

出　　处：《临床精神医学杂志》2002年第6期332-333,共2页Journal of Clinical Psychiatry

摘　　要：目的 :研究躁狂症患者外周血T淋巴细胞亚群及其相关因素。　方法 :收集 32例躁狂症患者和 30名健康对照者 ,采外周血作T淋巴细胞亚群测定 ,躁狂症组同时进行家族史、临床类型及简明精神病评定量表 (BPRS)、Bech Rafaelsen躁狂量表 (BRMS)评定。　结果 :躁狂症患者T淋巴细胞亚群中CD3 细胞数显著高于对照组。而与性别、家族史及临床类型无关。　结论 :躁狂症患者细胞免疫功能活跃 ,精神 神经Objective:To study on T cell subpopulation and related factors in manic patients. Method:32 manic inpatients and 30 normal controls were included in this study. T cell subpopulation levels were detected,at the same time,family history of psychiatric disorders, clinical subtypes,scales of BPRS and BRMS were assessed. Results:CD 3 subpopulations in blood were significantly higher in manic patients. Among different clinical subtypes,different positive family history or different sex, there were no differences of T cell subpopulations in all manic patients. Conclusion:Functions of cellular immunity are active in manics. Complex correlations may exist among mental, nervous and immune systems.

关 键 词：躁狂症 T淋巴细胞 细胞免疫 

分 类 号：R749.41[医药卫生—神经病学与精神病学]