原发性肾病综合征肾血流动力学多普勒超声研究  

Detection of Renal Hemodynamic Changes in Patients with Primary Nephrotic Syndrome by Doppler Ultrasonography

作　　者：张宁[1] 王智[2] 郑京[2] 丘余良[2] 洪江淮[2] 吴竞[2] 

机构地区：[1]福建省人民医院B超室,福州3500041 [2]福建省人民医院肾内科,福州3500041

出　　处：《福建医科大学学报》2002年第4期404-405,共2页Journal of Fujian Medical University

基　　金：福建省卫生厅科研基金资助项目 (9612 3)

摘　　要：目的　探讨原发性肾病综合征 (PNS)患者肾血流动力学多普勒超声变化的特征及临床意义。　方法　 76例经临床、肾穿病理证实的 PNS患者分成两组 :甲组 4 0例 (未治疗者 ) ,乙组 36例 (经治疗症状改善但仍未完全缓解者 )。另有 4 0例健康人作为对照组。应用脉冲多普勒超声 (PW)观察肾段动脉血流的收缩期最大流速 (Vs)、舒张期末速度 (Vd)、平均速度 (Vm)、搏动指数 (PI)、阻力指数 (RI)。　结果　甲、乙组与对照组间三项参数 (Vs、PI、RI)差异有显著性 ,但甲、乙组间比较差异无显著性。　结论　多普勒超声可评价 PNS患者的肾血流动力学变化特征 ,为临床Objective\ To investigate the characters of renal hemodynamic changes of primary nephrotic syndrome(PNS) by Doppler ultrasonography.\ Methods\ 76 patients with PNS confirmed clinically and by renal biopsy pathology and 40 normal subjects were recruited in this study.\ Seventy\|six patients were divided into two groups: group A consisted of 40 patients without therapeutics,and group B had 36 patients who were treated with incomplete remission of symptoms.\ Five renal artery homodynamic parameters including peak systolic flow velocity(Vs), end\|diastolic flow velocity(Vd), average flow velocity(Vm), pulse index(Pl) and resistance index(Rl) were measured by pulsed\|wave Doppler(PW).\ Results\ There were significant difference in three parameters(Vs, Pl and Rl) between patients and normal subjects, without any difference in the three parameters between group A and B.\ Conclusion\ Doppler ultrasonography is useful to detect renal hemodynamic changes in patients with PNS, and helpful in noninvasive diagnosis and follow\|up of PNS. \;

关 键 词：原发性肾病综合征 多普勒超声 超声检查 血流动力学 PNS 

分 类 号：R692[医药卫生—泌尿科学] R445.1[医药卫生—外科学]