EB病毒NA1-IgA联合VCA-IgA检测对鼻咽癌患者的临床诊断效能分析  

Analysis of Clinical Diagnostic Efficacy of EB Virus NA1-IgA Combined with VCA-IgA Detection on Patients with Nasopharyngeal Carcinoma

作　　者：覃卫洪 QIN Weihong(Hechi People's Hospital,Hechi 547000,China)

机构地区：[1]河池市人民医院,广西河池547000

出　　处：《中外医学研究》2024年第35期82-86,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析EB病毒NA1-IgA联合VCA-IgA检测对鼻咽癌患者的临床诊断效能。方法:回顾性分析2021年1月1日—2023年7月26日河池市人民医院住院、门诊检测鼻咽癌两项(EB病毒NA1-IgA、VCA-IgA)常规的783例患者血液标本。所有标本进行EB病毒NA1-IgA、VCA-IgA检测。比较NA1-IgA及VCA-IgA及两项联合阳性患者中鼻咽癌检出率。分析NA1-IgA及VCA-IgA联合诊断鼻咽癌的情况。结果:783例患者中NA1-IgA阳性155例(19.80%),VCA-IgA阳性114例(14.56%),NA1-IgA及VCA-IgA均阳性85例(10.86%)。NA1-IgA及VCA-IgA两项均为阳性患者中鼻咽癌检出率明显高于NA1-IgA及VCA-IgA单独阳性患者,差异有统计学意义(P<0.05)。NA1-IgA联合VCA-IgA诊断鼻咽癌的敏感度为98.67%(74/75),特异度为90.00%(9/10),准确度为97.65%(83/85)。结论:EB病毒NA1-IgA及VCA-IgA的联合检测对鼻咽癌患者的临床诊断效能较高。Objective:To analyze the clinical diagnostic efficacy of EB virus NA1-IgA combined with VCA-IgA detection on patients with nasopharyngeal carcinoma.Method:Blood samples of 783 patients undergoing nasopharyngeal carcinoma two items(EB virus NA1-IgA and VCA-IgA)routine were retrospectively analyzed from January 1,2021 to July 26,2023 in the inpatient and outpatient of Hechi People's Hospital.All samples were detected by EB virus NA1-IgA and VCA-IgA.The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA and its combined positive was compared.The diagnosis condition of nasopharyngeal carcinoma by NA1-IgA and VCA-IgA combination was analyzed.Result:Among the 783 patients,155 cases(19.80%)were NA1-IgA positive,114 cases(14.56%)were VCA-IgA positive,and 85 cases(10.86%)were both NA1-IgA and VCA-IgA positive.The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA positive patients was significantly higher than that in NA1-IgA and VCA-IgA alone positive patients,and the differences were statistically significant(P<0.05).The sensitivity,specificity and accuracy of NA1-IgA combined with VCA-IgA in diagnosis of nasopharyngeal carcinoma were 98.67%(74/75),90.00%(9/10)and 97.65%(83/85)respectively.Conclusion:The combined detection of EB virus NA1-IgA and VCA-IgA has high clinical diagnostic efficacy in patients with nasopharyngeal carcinoma.

关 键 词：EB病毒NA1-IgA VCA-IGA 鼻咽癌 临床诊断效能 

分 类 号：R73[医药卫生—肿瘤]