球拍形切口乳房成形术对乳腺癌患者应激反应及乳房美容效果的影响  

Effect of racket-shaped incision mammoplasty on stress response and breast beauty in patients with breast cancer

作　　者：关华鹤[1] 赵北永 邝亚辉 GUAN Huahe;ZHAO Beiyong;KUANG Yahui(Department of Thyroid and Breast Surgery,Zhoukou Central Hospital,Zhoukou 466000,He’nan,China)

机构地区：[1]周口市中心医院甲状腺乳腺外科,河南周口4660000

出　　处：《癌症进展》2024年第23期2654-2657,共4页Oncology Progress

摘　　要：目的探讨球拍形切口乳房成形术(RSIM)对乳腺癌患者应激反应及乳房美容效果的影响。方法根据手术方式的不同将103例患者分为RSIM组(n=52)和保乳组(n=51),保乳组患者接受常规保乳手术治疗,RSIM组患者接受RSIM手术。比较两组患者的应激反应指标[晚期氧化蛋白产物(AOPP)、超氧化物歧化酶(SOD)和皮质醇]、乳房美容效果[乳房整形者生活质量测定量表(BREAST-Q)]、围手术期指标及术后并发症发生情况。结果术后,两组患者AOPP、皮质醇水平均高于本组术前,SOD水平均低于本组术前,RSIM组患者AOPP、皮质醇水平均低于保乳组,SOD水平高于保乳组,差异均有统计学意义(P<0.05)。术后,RSIM组患者乳头横向偏移距离、质地与弹性、乳头纵向偏移距离、对成型、凹陷程度、皮肤颜色评分均明显高于保乳组,差异均有统计学意义(P<0.01)。RSIM组患者手术时间长于保乳组,并发症总发生率低于保乳组,差异均有统计学意义(P<0.05)。结论与常规保乳手术相比,RSIM手术能够更好地减轻乳腺癌患者的应激反应,提高乳房美容效果,减少术后并发症,但延长了手术时间。Objective To investigate the effect of racket-shaped incision mammoplasty(RSIM)on stress response and breast beauty in patients with breast cancer.Method According to different surgical methods,103 breat cancer pa-tients were divided into RSIM group(n=52)and breast conserving group(n=51).Patients in the breast conserving group received routine breast conserving surgery,while patients in the RSIM group received RSIM surgery.The stress response indicators[advanced oxidation protein product(AOPP),superoxide dismutase(SOD),and cortisol],breast cosmetic ef-fects[breast-questionnaire(BREAST-Q)],perioperative indicators,and incidence of postoperative complications were compared between the two groups.Result After surgery,the levels of AOPP and cortisol in both groups were higher than those before surgery,the levels of SOD were lower than those before surgery,the levels of AOPP and cortisol in RSIM group were lower than those in breast conserving group,and the level of SOD was higher than that in breast con-serving group,and the differences were statistically significant(P<0.05).After surgery,the scores of nipple lateral dis-placement distance,texture and elasticity,nipple longitudinal displacement distance,shaping,indentation degree,and skin color in RSIM group were higher than those in breast conserving group,and the differences were statistically significant(P<0.01).The surgery time in the RSIM group was longer than that in breast conserving group,and the total incidence of complications was lower than that in breast conserving group,and the differences were statistically significant(P<0.05).Conclusion Compared with routine breast conserving surgery,RSIM surgery can better reduce the stress reaction of breast cancer patients,improve the breast beauty effect,reduce postoperative complications,but prolong the operation time.

关 键 词：球拍形切口乳房成形术 常规保乳术 乳腺癌 应激反应 并发症 

分 类 号：R737.9[医药卫生—肿瘤]