整形保乳术联合腋窝淋巴结清扫术对乳腺癌患者并发症发生率及复发率的影响  

The impact of breast conserving surgery combined with modified radical mastectomy and axillary lymph node dissection on the incidence of complications and recurrence in breast cancer patients

作　　者：翟新菊 李红涛[1] 管钰琳 司海燕[1] ZHAI Xinju;LI Hongtao;GUAN Yulin;SI Haiyan(Comprehensive Surgery of Breast and Thyroid Gland,Jiaozuo People's Hospital,Henan Province,454000,China)

机构地区：[1]焦作市人民医院乳腺甲状腺综合外科,河南焦作454000

出　　处：《中国医疗美容》2024年第12期54-57,共4页China Medical Cosmetology

基　　金：河南省医学科技攻关联合共建项目(LHGJ20221091)。

摘　　要：目的回顾性对比分析整形保乳术与改良根治术分别联合腋窝淋巴结清扫术(ALNB)对乳腺癌患者并发症发生率及复发率的影响。方法回顾性选取本院2020年11月至2022年11月于焦作市人民医院就诊的80例乳腺癌患者,每组40例。对照组患者将采用改良根治术联合ALNB治疗,观察组患者采用整形保乳术联合ALNB治疗。比较患者手术指标、手术前后癌胚抗原相关细胞黏附分子1(CEACAM1)、肿瘤相关物质(BXTM)、癌胚抗原(CEA)水平;肩部活动度、美容效果、生活质量、并发症及复发率。结果与对照组相比,观察组患者的出血量更少、腋窝拔管时间及手术时间更短、腋窝引流量较少,差异有统计学意义(P<0.05);与术前相比,术后1周两组CEACAM1、BXTM、CEA均显著改善,差异有统计学意义(P<0.05);术后6个月,观察组患者肩部活动度优于对照组,差异有统计学意义(P<0.05);术后6个月,两组患者术后美容效果比较,差异无统计学意义(P>0.05);两组患者并发症发生率比较,差异无统计学意义(P>0.05)。结论乳腺癌患者行整形保乳术联合ALNB治疗能改善肩部活动度,提高生活质量,促进患者快速恢复。Objective To retrospectively compare and analyze the impact of breast conserving surgery combined with modified radical mastectomy(Axillary lymph nodes dissection,ALNB)on the incidence of complications and recurrence rate in breast cancer patients.Methods A retrospective study was conducted on 80 breast cancer patients who were treated at Jiaozuo People's Hospital from November 2020 to November 2022,with 40 patients in each group.Patients in the control group will undergo modified radical mastectomy combined with ALNB,while patients in the observation group will undergo plastic breast conserving surgery combined with ALNB.The surgical indicators,CEACAM1,BXTM,CEA,shoulder mobility,cosmetic effect,quality of life,complications,and recurrence rate were compared.Results Compared with the control group,the observation group had less bleeding,shorter axillary extubation and surgery time,and less axillary drainage volume,with statistically significant differences(P<0.05);Compared with preoperative levels,CEACAM1,BXTM,and CEA in both groups showed significant improvement one week after surgery,with statistically significant differences(P<0.05);Six months after surgery,the shoulder mobility of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05);Six months after surgery,there was no statistically significant difference in postoperative cosmetic effects between the two groups of patients(P>0.05);There was no statistically significant difference in the incidence of complications between the two groups of patients(P>0.05).Conclusions Breast cancer patients undergoing plastic breast-conserving surgery combined with ALNB treatment can improve shoulder mobility,enhance quality of life,and promote rapid recovery.

关 键 词：乳腺癌 腋窝淋巴结清扫术 并发症 复发率 整形保乳术 

分 类 号：R73[医药卫生—肿瘤]