低频重复经颅脑刺激联合针刺法治疗脑梗死后淡漠综合征的效果  

Effect of Low-Frequency Repetitive Transcranial Stimulation Combined with Acupuncture in the Treatment of Apathy Syndrome After Cerebral Infarction

作　　者：李阳阳[1] 刘欣欣[1] LI Yangyang;LIU Xinxin(Department of Geriatrics Neurology,the First Affiliated Hospital of Henan University,Kaifeng 475000,China)

机构地区：[1]河南大学第一附属医院老年神经内科,河南开封475000

出　　处：《河南医学研究》2025年第1期80-84,共5页Henan Medical Research

基　　金：2021年河南省医学科技攻关计划联合共建项目(LHGJ20210562)。

摘　　要：目的探讨低频重复经颅磁刺激(rTMS)联合针刺法对脑梗死后淡漠综合征(PSA)的康复效果。方法选取2020年11月至2021年12月在河南大学第一附属医院老年神经内科住院的84例脑梗死后淡漠综合征的患者为研究对象,按照随机数字表法分为对照组和试验组,每组42例,在常规治疗、康复及护理干预的基础上,对照组接受低频rTMS治疗,试验组接受rTMS联合针刺法治疗,干预周期均为4周,使用淡漠评定量表-知情者版(AES-I)评估干预后患者淡漠水平改善情况,另外通过脑卒中专门化生存质量量表(SS-QOL)和改良Barthel指数(MBI)以及简易智能精神状态检查量表(MMSE)对两组患者日常生活质量和生活能力以及认知功能进行评价。结果79例完成干预,两组患者一般资料差异无统计学意义(P>0.05)。两组干预前的AES-I得分差异无统计学意义(P>0.05)。两组干预后的AES-I总分降低,试验组更低(P<0.05)。干预后试验组兴趣、认知和行为得分减少(P<0.05);情感得分也减少,但和对照组的差异无统计学意义(P>0.05)。干预后,两组MBI评分升高,但与干预前差异无统计学意义(P>0.05)。两组干预前的SS-QOL评分差异无统计学意义(P>0.05),两组干预后SS-QOL评分升高,试验组更高(P<0.05)。干预前,两组MMSE评分差异无统计学意义(P>0.05),干预后,两组MMSE评分升高,试验组更高(P<0.05)。结论针刺法与低频rTMS疗法联合应用于卒中后淡漠综合征的患者康复治疗中,能有效改善患者的生活质量和认知功能,降低卒中后淡漠症状水平。Objective To investigate the effect of repeat transcranial magnetic stimulation(rTMS)combined with acupuncture on the rehabilitation of post-stroke apathy syndrome(PSA).Methods A total of 84 patients with post-cerebral infarction indifference syndrome hospitalized in the Department of Geriatrics Neurology of the First Affiliated Hospital of Henan University from November 2020 to December 2021 were selected as research objects,and divided into control group and experimental group according to the random number table method,with 42 cases in each group.On the basis of routine treatment,rehabilitation and nursing intervention,the control group was treated with low frequency rTMS,and the experimental group was treated with rTMS combined with acupuncture.The intervention cycles were all 4 weeks,using apathy evaluation scale-informant(AES-I)evaluated the improvement of the patients’insensitive level after the intervention,and the daily life quality,living ability and cognitive function of the patients in both groups were evaluated by stroke specialized quality of life scale(SS-QOL),modified Barthel index(MBI)and mini-mental state examination scale(MMSE).Results A total of 79 patients completed the intervention.There was no statistically difference in general information between the two groups of patients(P>0.05).There was no statistically difference in AES-I scores between the two groups before intervention(P>0.05).After intervention,the total score of AES-I decreased in both groups,with the experimental group had lower score(P<0.05).After intervention,the interest,cognition,and behavior scores of the experimental group decreased(P<0.05).The emotional score also decreased,but there was no statistically difference compared to the control group(P>0.05).After intervention,the MBI scores of both groups increased,but there was no statistically difference compared to before intervention(P>0.05).There was no statistically difference in SS-QOL scores between the two groups before intervention(P>0.05).After intervention,the SS

关 键 词：脑梗死 淡漠综合征 重复经颅磁刺激 针刺法 

分 类 号：R743.3[医药卫生—神经病学与精神病学]