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作 者:刘涛 莫霖[1] 沈雨晴 陈泽方 LIU Tao;MO Lin;SHEN Yuqing;CHEN Zefang(Out-patient Department,Children's Hospital of Chongqing Medical University,Chongqing 400014,China)
机构地区:[1]重庆医科大学附属儿童医院门诊部,重庆400014
出 处:《现代肿瘤医学》2025年第1期128-133,共6页Journal of Modern Oncology
基 金:国家自然科学基金面上项目(编号:72474040);重庆市自然科学基金面上项目(编号:CSTB2022NSCQ-MSX0082);重庆医科大学智慧医学研究项目(编号:ZHYX202225)。
摘 要:恶性肿瘤是我国儿童死亡的第二大原因,尽管近十年来在儿童肿瘤诊断和治疗等方面取得了较大进步,但肿瘤本身及其相关治疗手段引发的肿瘤相关认知障碍(cancer-related cognitive impairment,CRCI)已成为恶性肿瘤患儿最严重的神经系统并发症之一,严重影响患儿的预后及生活质量。该文对儿童CRCI的特点、评估工具及常用的非药物干预方法等进行综述,并提出了相关的建议,以期为儿童CRCI的早期识别与干预提供参考依据。Malignant tumors are the second leading cause of death among children in China.Although great progress has been made in the diagnosis and treatment of childhood tumors in the past decade,cancer-related cognitive impairment(CRCI)caused by tumors themselves and related treatments has become one of the most serious neurological complications in children with malignant tumors,seriously affecting their prognosis and quality of life.In this paper,the characteristics,evaluation tools and common non-drug intervention methods of children's CRCI were reviewed,and relevant suggestions were put forward to provide reference for early identification and intervention of children's CRCI.
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