阿尔茨海默病的治疗进展  

Advances in Treatment of Alzheimer′s Disease

作　　者：马清清 李宗友[1] 朱增光 MA Qingqing;LI Zongyou;ZHU Zengguang(Department of Neurology,Ward One,Fuyang People′s Hospital,Fuyang 236000,China;Department of Medical Oncology,Ward One,Affiliated Hospital of Qinghai University,Xining 810000,China)

机构地区：[1]阜阳市人民医院神经内科一病区,安徽阜阳236000 [2]青海大学附属医院肿瘤内科一病区,西宁810000

出　　处：《医学综述》2025年第3期313-318,共6页Medical Recapitulate

摘　　要：阿尔茨海默病(AD)是一种神经系统退行性疾病,随着人口老龄化的加剧,其发病率在全球范围内呈逐年递增趋势。目前AD的发病机制主要包括β淀粉样蛋白学说、tau蛋白学说以及氧化应激学说。近年来,人们对AD的认知不断提升,其治疗方法主要包括西医治疗、中医治疗(如针灸、推拿)、物理疗法、饮食疗法等,其中越来越多针对AD病因的单抗类药物、靶向药物使更多患者获得了满意的效果。随着医疗的进步与发展,相信会有更多的靶向、单抗类研究药物使患者获益。Alzheimer′s disease(AD)is a degenerative disease of the nervous system.With the increase of population aging,its incidence is increasing year by year worldwide.At present,the pathogenesis of AD mainly includes amyloidβ-protein theory,tau protein theory and oxidative stress theory.In recent years,people′s awareness of AD has been continuously improved,and its treatment methods mainly include western medicine treatment,traditional Chinese medicine treatment(such as acupuncture and massage),physical therapy,diet therapy,etc.,among which more and more monoclonal antibody drugs and targeted drugs targeting the causes of AD have achieved satisfactory results in more patients.With the progress and development of the medical treatment,it is believed that there will be more targeted and monoclonal antibody drugs under research to benefit the patients.

关 键 词：阿尔茨海默病 发病机制 西医治疗 中医治疗 

分 类 号：R741[医药卫生—神经病学与精神病学]