Retinal capillary density among healthy Egyptian and South Asian students:an optical coherence tomography angiography study  

作　　者：Abdussalam M Abdullatif Alimulhaq Mohammad Moamnlhaq Tamer A.Macky Noha Ahmed Edris 

机构地区：[1]Department of Ophthalmology,Kasr ElAini Hospital,Cairo University,Cairo 1141,Egypt

出　　处：《International Journal of Ophthalmology(English edition)》2025年第1期111-116,共6页国际眼科杂志(英文版)

摘　　要：AIM:To compare the macular and optic nerve perfusion and vascular architecture using optical coherence tomography angiography(OCTA)in normal eyes of Egyptian(Caucasians)and South Asian(Asians)volunteers.METHODS:Cross-sectional analytical OCTA study performed on 90 eyes of South Asian(n=45)and Egyptians(n=45)were analyzed.All participants underwent bestcorrected visual acuity test,slit lamp,and fundus examination.OCTA images;macular 6×6 mm^(2) grid and optic nerve 4.5×4.5 mm^(2) grid were used to examine the parafoveal and peripapillary regions,respectively.RESULTS:The mean capillary vessel density(CVD)in macular sectors among South Asians and Egyptians participants were(50.31%±2.53%,51.2%±5.93%)and(49.71%±3.6%,51.94%±4.79%)in superficial(SCP)and deep capillary plexuses(DCP),respectively(P>0.05).Mean CVD in both groups was higher in DCP compared to SCP in all sectors but was not significant(P>0.05).Mean foveal CVD increases with an increase in central retinal thickness in both SCP and DCP(P<0.001),among both groups.Mean area of the foveal avascular zone(FAZ)was 0.28±0.09 and 0.27±0.08 mm2 in South Asian and Egyptians,respectively.FAZ area decreases with an increase in the thickness and foveal CVD(P<0.001).Mean CVD in the peripapillary area was 48.23%±5.78% in South Asian and 49.52%±2.38% in Egyptian volunteers.The mean retinal nerve fiber layer thickness was found to be higher in the nasal quadrant among South Asian females than the Egyptian females(P<0.05).CONCLUSION:No significant racial disparity is found in this study.The findings are helpful for assessing and improving the normative data on the differences in South Asian and Egyptian populations.

关 键 词：South Asian EGYPTIAN optical coherence tomography angiography macular perfusion peripapillary vessel flow density 

分 类 号：R774.6[医药卫生—眼科]