3~5岁儿童口腔白色念珠菌分布现状及其与龋病的关系研究  

Study on current distribution of oral Candida albicans and its relationship with caries in children aged 3~5 years old

作　　者：张宁 Zhang Ning(Maternal and Child Health and Family Planning Service Center,Tianjin Binhai New Area,Tianjin 300450,China)

机构地区：[1]天津市滨海新区妇幼保健计划生育服务中心,天津300450

出　　处：《齐齐哈尔医学院学报》2025年第1期70-75,共6页Journal of Qiqihar Medical University

摘　　要：目的探究3~5岁儿童口腔白色念珠菌分布现状及其与龋病的关系。方法采用随机抽样方法于2023年6—8月在本院附近的3所幼儿园中各选取85名3~5岁儿童,共计255名作为研究对象。参照《第三次全国口腔健康流行病学调查方案》的学龄前儿童问卷,并结合地方特点进行改编进行问卷调查,根据是否检查出白色念珠菌分为检出组和未检出组,再依据有无龋病,将儿童归入龋病组或非龋病组。观察白色念珠菌及龋病分布情况,分析牙菌斑中白色念珠菌检出情况及患龋情况,再通过Logistic回归分析白色念珠菌及患龋的影响因素。结果(1)在纳入的255名儿童中,有82名儿童检出有白色念珠菌,其检出率为32.16%(82/255);有155名儿童患龋,患龋率为60.78%(155/255);(2)牙菌斑中白色念珠菌检出情况中随着儿童年龄的增长,其检出率也逐渐增加,3岁占比26.83%,4岁占比32.93%,5岁占比40.24%。其中男童占比为52.44%,略高于女童占比(47.56%)。两组年龄、性别、家长学历、家庭月收入、吃甜食频率、是否使用含氟牙膏比较,差异无统计学意义(P>0.05),睡前吃甜食、刷牙次数比较,差异具有统计学意义(P<0.05);(3)进行Logistic回归分析,结果显示,睡前吃甜食、刷牙次数是牙菌斑中白色念珠菌检出的危险因素(P<0.05);(4)两组年龄、性别、家长学历、家庭月收入、吃甜食频率、是否使用含氟牙膏比较,差异无统计学意义(P>0.05),刷牙次数、睡前吃甜食、白色念珠菌检出情况比较,差异具有统计学意义(P<0.05);(5)进行Logistic回归分析,结果显示,睡前吃甜食、刷牙次数≤1次/d、白色念珠菌检出占比较高是龋病的危险因素(P<0.05)。结论睡前吃甜食、刷牙次数是牙菌斑中白色念珠菌检出的危险因素,而睡前吃甜食、刷牙次数≤1次/d、白色念珠菌检出占比较高是龋病的危险因素,睡前摄取甜食的习惯,可能会加速白色念珠菌在3~5岁儿�Objective To explore the current distribution of oral candida albicans in children aged 3 to 5 years and its relationship with dental caries.Methods A random sampling method was used to select 85 children aged 3 to 5 years from each of the three kindergartens near our hospital,totaling 255 children,as the subjects of this study from June to August 2023.A questionnaire for preschool children was adapted from the Third National Oral Health Epidemiological Survey Program and modified to fit local characteristics.Children were divided into detected and non-detected groups based on the presence of candida albicans and then into caries and non-caries groups based on the presence of dental caries.We observed the distribution of candida albicans and caries,analyzed the detection of candida albicans in dental plaque and the prevalence of caries,and then used logistic regression to analyze the influencing factors of candida albicans and caries.Results Of the 255 children included,82 were detected with candida albicans,with a detection rate of 32.16%(82/255);155 children had dental caries,with a caries rate of 60.78%(155/255).The detection rate of candida albicans in dental plaque increased with age,with 3-year-olds at 26.83%,4-year-olds at 32.93%,and 5-year-olds at 40.24%.Boys accounted for 52.44%,slightly higher than girls at 47.56%.There were no statistically significant differences in age,gender,parental education,monthly family income,frequency of sweet consumption,or use of fluoride toothpaste between the groups(P>0.05),but there were significant differences in the frequency of eating sweets before bedtime and the number of times teeth were brushed(P<0.05).Logistic regression analysis showed that eating sweets before bedtime and the number of times teeth were brushed were risk factors for the detection of candida albicans in dental plaque(P<0.05).There were no significant differences in age,gender,parental education,monthly family income,frequency of sweet consumption,or use of fluoride toothpaste(P>0.05),but there we

关 键 词：3~5岁儿童 口腔白色念珠菌 分布现状 龋病 

分 类 号：R788.1[医药卫生—口腔医学]