康复训练对晚期肺癌放疗患者心肺功能及运动耐量的影响  

Effects of rehabilitation training on cardiopulmonary function and exercise tolerance in patients with advanced lung cancer undergoing radiotherapy

作　　者：杨雪[1] 杨平平 李爱君[2] 赵大奇[1] YANG Xue;YANG Ping-ping;LI Ai-jun(Chemotherapy Department,High-Tech Hospital of Tai'an Central Hospital,Tai'an 271000,China)

机构地区：[1]泰安市中心医院高新院区化疗科,271000 [2]泰安市中心医院分院护理部,271000

出　　处：《中国现代药物应用》2024年第24期151-154,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析康复训练对晚期肺癌放疗患者心肺功能及运动耐量的影响。方法100例拟行放疗的晚期肺癌患者,根据患者入院先后顺序编号分组,单号者纳入康复训练组,双号者纳入对照组,每组50例。两组均行肺癌常规放疗,康复训练组在此基础上给予康复训练。比较两组干预前后肺功能[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC]、心功能[左室射血分数(LVEF)和左室舒张末期内径(LVEDD)、二尖瓣口舒张早期与晚期最大速度比值(E/A)]和运动耐量[6 min步行距离(6MWD)、呼吸困难程度、血氧饱和度(SpO2)、脉搏频率(PR)]。结果干预后,与对照组的(2.11±0.53)、(2.97±0.76)L相比,康复训练组患者FEV1(2.38±0.57)L、FVC(3.28±0.67)L均明显提高(P<0.05);两组FEV1/FVC水平比较差异无统计学意义(P>0.05)。干预后,两组LVEF、LVEDD、E/A均较干预前明显改善,且与对照组的(50.19±4.58)%、(1.21±0.20)、(55.73±4.68)mm相比,康复训练组LVEF(53.52±4.47)%、E/A(1.47±0.15)均明显提升,LVEDD(53.15±3.51)mm明显下降(P<0.05)。干预后,康复训练组6MWD、Borg评分、SpO2、PR均较干预前明显改善(P<0.05);且与对照组的(375.22±17.23)m、(97.14±0.87)%、(0.87±0.36)分、(87.04±3.57)次/min相比,康复训练组6MWD(387.16±17.08)m、SpO2(98.12±0.85)%均明显提高,Borg评分(0.58±0.35)分、PR(83.02±3.86)次/min均明显降低(P<0.05)。结论康复康复训练可有效提高晚期肺癌放疗患者的心肺功能和运动耐量。Objective To analyze the effects of rehabilitation training on cardiopulmonary function and exercise tolerance in patients with advanced lung cancer undergoing radiotherapy.Methods 100 patients with advanced lung cancer who were scheduled for radiotherapy were numbered according to the order of admission.Those with odd number were included in the rehabilitation training group,and those with even number were included in the control group,with 50 cases in each group.Both groups were treated with conventional radiotherapy for lung cancer,and the rehabilitation training group was given rehabilitation training on this basis.Both groups were compared in terms of lung function[force expiratory volume in one second(FEV1),forced vital capacity(FVC),FEV1/FVC],cardiac function[left ventricular ejection fraction(LVEF)and left ventricular end-diastolic diameter(LVEDD),ratio of early transmitral flow velocity to later transmitral flow velocity(E/A)]and exercise tolerance[6-min walking distance(6MWD),dyspnea degree,oxygen saturation(SpO_(2)),pulse rate(PR)]before and after the intervention.Results After the intervention,FEV1(2.38±0.57)L and FVC(3.28±0.67)L in the rehabilitation training group were significantly higher than(2.11±0.53)and(2.97±0.76)L in the control group(P<0.05).The difference in FEV1/FVC between the two groups was not statistically significant(P>0.05).After the intervention,LVEF,LVEDD and E/A were significantly improved in both groups compared with those before the intervention;compared with(50.19±4.58)%,(1.21±0.20),and(55.73±4.68)mm in the control group,LVEF(53.52±4.47)%and E/A(1.47±0.15)in the rehabilitation training group were significantly elevated,and LVEDD(53.15±3.51)mm was significantly decreased(P<0.05).After the intervention,the 6MWD,Borg score,SpO_(2),and PR were significantly improved in the rehabilitation training group compared with those before the intervention(P<0.05).Compared with(375.22±17.23)m,(97.14±0.87)%,(0.87±0.36)points,and(87.04±3.57)beats/min in the control group,the 6MWD(3

关 键 词：康复训练 晚期肺癌 放疗 心肺功能 运动耐量 

分 类 号：R73[医药卫生—肿瘤]