Acute Recruitment of VTA Dopamine Neurons by mPOA Esr1+Neurons to Facilitate Consummatory Male Mating Actions  

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作  者:Zhuo-Lei Jiao Min Zhang Ya-Nan Wu Shuai-Shuai Li Meng-Tong Gao Wen Zhang Xiao-Hong Xu 

机构地区:[1]Institute of Neuroscience,Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai,200031,China [2]University of Chinese Academy of Sciences,Beijing,100049,China

出  处:《Neuroscience Bulletin》2024年第11期1745-1750,共6页神经科学通报(英文版)

基  金:supported by grants from STI 2030-Major Projects(2021ZD0203203,2021ZD02044400);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32000000);the National Natural Science Foundation of China(31871066,31922028,and 31900721);the Shanghai Municipal Science and Technology Major Project(2018 SHZDZX05).

摘  要:Dear Editor,Instinctual male mating actions serve the fundamental purpose of bringing the two gametes together in sexually reproducing species[1,2].Upon encountering a conspecific female,a male mouse investigates the female's body and external genital regions.Subsequently,the male mouse may mount the female and initiate rhythmic pelvic thrusts(intromission),leading to ejaculation and sperm transfer after several cycles.Notably,in mice,the transition from investigatory behaviors to consummatory mating actions,such as mounting and intromission,occurs stochastically and non-deterministically,marked by considerable inter-individual and intra-trial variability.Moreover,there is a gradual decline in the proportion of males progressing to successive mating stages-from social investigation to mount,intromission,and ejaculation-within a given trial.

关 键 词:MOUNT DOPAMINE bringing 

分 类 号:R338.6[医药卫生—人体生理学]

 

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