分离手术治疗腰椎转移性肿瘤的临床疗效研究  

Clinical effect of separation surgery on metastatic tumors of lumbar spine

作　　者：孙敏 江正[1] 徐生林[1] 曹坤[1] 胡勇[1] SUN Min;JIANG Zheng;XU Sheng-lin;CAO Kun;HU Yong(Department of Osteopathy and Bone Oncology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 231200,China)

机构地区：[1]安徽医科大学第一附属医院骨病骨肿瘤科,安徽合肥231200

出　　处：《颈腰痛杂志》2024年第6期1051-1054,共4页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的回顾性分析分离手术治疗腰椎转移性肿瘤的临床疗效。方法本研究回顾性分析安徽医科大学第一附属医院2018年1月至2023年12月行分离手术治疗的腰椎转移瘤患者46例,分析比较手术时间、术中出血量及术后切口拆线时间,并于术前及术后2周、1个月、3个月、6个月行VAS、KPS评分及Frankel分类评估。结果46例患者手术均顺利完成,术前及术后2周、1个月、3个月、6个月的VAS评分分别为(8.27±0.23)、(4.27±0.49)、(3.00±0.82)、(2.71±0.49)、(2.16±0.21)分,各时间点疼痛评分均较术前有所降低,差异有统计学意义(P<0.05);术后KPS评分情况:术前及术后2周、1个月、3个月、6个月KPS分值分别为(36.78±0.36)、(49.27±0.11)、(52.09±0.36)、(61.31±0.24)、(70.16±0.23)分,术后KPS评分均较术前有所提高,差异有统计学意义(P<0.05)。结论分离手术已成为腰椎转移瘤的有效治疗方式,可早期有效缓解疼痛、提高患者的生存质量,能在一定程度上控制局部病灶的进展。Objective To retrospectively analyze the clinical effect of separation surgery on metastatic tumors of lumbar spine.Methods A total of 46 patients with lumbar metastases who received separation surgery in the First Affiliated Hospital of Anhui Medical University from January 2018 to December 2023 were retrospectively studied.The operative time,intraoperative blood loss and postoperative incision removal time were analyzed and compared.VAS,KPS scores and Frankel classification were evaluated before surgery and after surgery at 2 weeks,1 month,3 months and 6 months.Results All 46 patients underwent surgery successfully.The VAS scores at preoperative,2 weeks,1 month,3 months,and 6 months postoperatively were(8.27±0.23),(4.27±0.49),(3.00±0.82),(2.71±0.49),and(2.16±0.21),respectively.Pain scores at each time point were significantly reduced compared to preoperative levels,with statistical significance(P<0.05).As for the KPS scores,the values at preoperative,2 weeks,1 month,3 months,and 6 months postoperatively were(36.78±0.36),(49.27±0.11),(52.09±0.36),(61.31±0.24),and(70.16±0.23),respectively.Postoperative KPS scores were significantly higher than preoperative levels,with statistical significance(P<0.05).Conclusion Separation surgery has become an effective way for lumbar metastatic tumors,which can effectively relieve pain in early stage,improve the quality of life of patients,and control the progression of local lesions to a certain extent.

关 键 词：腰椎 脊柱肿瘤 转移瘤 分离手术 

分 类 号：R73-37[医药卫生—肿瘤]