临床药师参与的综合用药干预在精神分裂症患者中的应用效果分析  

Analysis of Application Effect of Comprehensive Medication Intervention Involving Clinical Pharmacists in Patients with Schizophrenia

作　　者：陈晓红 Chen Xiaohong(Department of Pharmacy,Xuzhou Tongshan District Jifu Hospital,Xuzhou221009,Jiangsu Province,China)

机构地区：[1]徐州市铜山区济复医院药剂科,江苏徐州221009

出　　处：《中国社区医师》2025年第1期6-8,共3页Chinese Community Doctors

摘　　要：目的:分析临床药师参与的综合用药干预在精神分裂症(SZ)患者中的应用效果。方法:选取2023年8月—2024年7月于徐州市铜山区济复医院接受治疗的SZ患者84例作为研究对象,采用随机数字表法分为对照组(n=42)与试验组(n=42)。对照组实施常规用药指导,试验组实施临床药师参与的综合用药干预。比较两组用药规范性、用药依从性、精神症状、不良反应发生情况。结果:干预后,两组用药规范性、用药依从性评分高于干预前,且与对照组比较,试验组更高(P<0.05)。干预后,两组阳性症状、阴性症状、一般精神病理评分及总分低于干预前,且与对照组比较,试验组更低(P<0.05)。与对照组比较,试验组不良反应总发生率更低(P=0.048)。结论:临床药师参与的综合用药干预SE患者中的应用效果显著,可提高患者的用药规范性及依从性,减轻精神症状,保障患者用药安全性。Objective:To analyze the application effect of comprehensive medication intervention involving clinical pharmacists in patients with schizophrenia(SZ).Methods:From August 2023 to July 2024,84 SZ patients who received treatment at Xuzhou Tongshan District Jifu Hospital were selected as the study subjects.They were divided into a control group(n=42)and an experimental group(n=42)using a random number table method.The control group received routine medication guidance,while the experimental group received comprehensive medication intervention involving clinical pharmacists.The medication standardization,medication adherence,psychiatric symptoms,and adverse reactions were compared between the two groups.Results:After the intervention,the scores of medication standardization and medication adherence in the two groups were higher than those before intervention,and the scores in the experimental group were higher than those in the control group(P<0.05).After intervention,the positive symptoms,negative symptoms,general psychopathological scores and total scores in the two groups were lower than those before intervention,and the scores in the experimental group were lower than those in the control group(P<0.05).The total incidence of adverse reactions in the experimental group was lower than that in the control group(P=0.048).Conclusion:The comprehensive medication intervention involving clinical pharmacists has a significant effect in the SE patients with schizophrenia,and can improve the medication standardization and adherence of patients,alleviate psychiatric symptoms,and ensure the medication safety of patients.

关 键 词：精神分裂症 临床药师 综合用药干预 

分 类 号：R749.3[医药卫生—神经病学与精神病学]