阿尔茨海默病中医药治疗进展  

Progress in the prevention and treatment of Alzheimer's disease with traditional Chinese medicine

作　　者：费尔立 顾耘[1] Erli FEI;Yun GU(Department of Geriatrics,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属龙华医院老年医学科,上海200032

出　　处：《阿尔茨海默病及相关病杂志》2025年第1期67-72,共6页Chinese Journal of Alzheimer's Disease and Related Disorders

基　　金：2022年上海市名老中医学术经验研究工作室建设项目(SHGZS-202241)。

摘　　要：阿尔茨海默病(Alzheimer's disease,AD)是一类主要表现为认知障碍的变性疾病,在全世界范围内影响超过了5000万人。近年来AD生物标志物和影像学诊断的研究进展为AD的早发现、早诊断带来了新的希望。脑肠轴等新的通路被发现,为我们带来了如GV-971等新药上市,为AD的治疗带来了新的选择。人类对AD的认识仍然是管中窥豹,冰山一角,中医的抗衰老优势在脑老化及AD的干预中显得尤为重要。AD在传统医学中归属于“痴呆”的范畴,传统医家与其已有超过一千年的抗争历史,因而中医对“痴呆”的治疗有着深刻的认识,许多中医理论与现代医学诸如脑肠轴等通路有不谋而合之处,通过现代医学发展再次探讨AD的中医治疗,能够为AD的中医治疗提供更多的依据与研究方向。Alzheimer's disease(AD)is a degenerative disease characterized by cognitive impairment,affecting over 50 million people worldwide.In recent years,the research progress of AD biomarkers and imaging diagnosis has brought new hope for the early detection and diagnosis of AD.The discovery of new pathways such as the brain-gut axis has led to the successful launch of new drugs such as GV-971,which has brought new options for the treatment of AD.But human understanding of AD is still the tip of the iceberg.Therefore,the anti-aging advantages of TCM are particularly important in the intervention of brain aging and AD.AD belongs to the category of"dementia"in traditional medicine,and traditional doctors have been fi ghting against it for more than 1,000 years,so TCM has a deep understanding of the treatment of"dementia",and many TCM theories coincide with modern medicine such as the brain-gut axis,which can provide more basis for the treatment of AD.

关 键 词：阿尔茨海默病 痴呆 中医治疗 

分 类 号：R74[医药卫生—神经病学与精神病学]