沙盘游戏疗法辅助治疗帕金森病合并抑郁患者的效果  

The effect of sandplay therapy for Parkinson's disease patients with depression

作　　者：贺婵婵 李珊 邓路路 杜培培 加艳 HE Chanchan;LI Shan;DENG Lulu(Yan'an University Xianyang Hospital,Xianyang 712000,China)

机构地区：[1]延安大学咸阳医院,咸阳712000

出　　处：《国际精神病学杂志》2024年第6期1846-1849,共4页Journal Of International Psychiatry

摘　　要：目的 分析帕金森病合并抑郁患者应用沙盘游戏疗法联合盐酸帕罗西汀治疗对不良心理状态、单胺神经递质水平及认知功能的影响。方法 将我院2021年8月~2023年8月期间收治的106例帕金森病合并抑郁患者纳入为研究对象,以随机数表法分为两组,各53例。对照组53例给予盐酸帕罗西汀治疗,研究组53例在此基础上增加沙盘游戏疗法。对比两组患者不良心理状态、单胺神经递质水平、认知功能、不良反应。结果 研究组患者焦虑自评量表评分、抑郁自评量表评分均低于对照组(P<0.05);研究组患者5-羟色胺、多巴胺、去甲肾上腺素水平均高于对照组(P<0.05);研究组患者定向力、记忆力、注意力和计算力、回忆能力、语言能力分值均高于对照组(P<0.05);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论 沙盘游戏疗法联合盐酸帕罗西汀治疗能够有效减轻帕金森病合并抑郁患者不良心理状态,提高单胺神经递质水平,改善认知功能,且安全性高。Objective To analyze the effects of sandplay therapy combined with paroxetine hydrochloride on adverse mental state,monoamine neurotransmitter level and cognitive function in patients with Parkinson's disease complicated with depression.Methods A total of 106 patients with Parkinson's disease combined with depression admitted to our hospital from August 2021 to August 2023 were included in the study,and were divided into two groups by random number table method,with 53 cases each.In the control group,53 cases were treated with paroxetine hydrochloride,and in the study group,53 cases were treated with sandplay therapy.The adverse psychological state,monoamine neurotransmitter level,cognitive function and adverse reactions were compared between the two groups.Results The scores of self-rating anxiety scale and self-rating depression scale in study group were lower than those in control group(P<0.05).The levels of serotonin,dopamine and norepinephrine in study group were higher than those in control group(P<0.05).The scores of orientation,memory,attention,calculation,recall and language ability in the study group were higher than those in the control group(P<0.05).paroxetine hydrochloride and(P>0.05).Conclusion Sandplay therapy combined with paroxetine hydrochloride can effectively reduce the adverse psychological state of patients with Parkinson's disease complicated with depression,suggest the level of monoamine neurotransmitter,improve cognitive function,and have high safety.

关 键 词：沙盘游戏疗法 盐酸帕罗西汀 帕金森病 抑郁 不良心理状态 单胺神经递质水平 认知功能 

分 类 号：R749.05[医药卫生—神经病学与精神病学]