体外循环心脏手术后早期谵妄的危险因素  

Investigation of risk factors for early delirium after extracorporeal circulation cardiac surgery

作　　者：王永坤 金辉[1] 吴留广[1] 胡有森 WANG Yongkun;JIN Hui;WU Liuguang(Zhoukou Central Hospital,Zhoukou 466000,China)

机构地区：[1]周口市中心医院,周口466000

出　　处：《国际精神病学杂志》2024年第6期1910-1912,共3页Journal Of International Psychiatry

摘　　要：目的 探讨体外循环心脏手术后早期谵妄的危险因素。方法 纳入周口市中心医院2020年4月~2022年6月84例采用体外循环心脏手术的心脏疾病患者,观察ICU治疗期间谵妄发生情况,比较谵妄与非谵妄患者病历资料,采用二元Logistic回归分析调查术后早期谵妄的危险因素。结果 84例患者中28例出现谵妄;谵妄组与非谵妄组在年龄、体外循环时间、ICU停留时间、合并焦虑情绪、睡眠障碍、合并低氧血症、使用苯二氮?类药物、机械通气时间差异具有统计学意义(P<0.05),两组在性别、疾病类型、合并糖尿病、合并高血压差异无统计学意义(P>0.05);二元Logistic回归分析显示体外循环时间、ICU停留时间、合并焦虑情绪、睡眠障碍、合并低氧血症、使用苯二氮?类药物是出现谵妄的危险因素。结论 体外循环心脏手术后早期容易发生谵妄,体外循环时间、ICU停留时间长等会增加谵妄风险。Objective To explore the risk factors of early delirium after extracorporeal circulation cardiac surgery.Methods Eighty-four heart disease patients who underwent extracorporeal circulation heart surgery in Zhoukou City Center Hospital from April 2020 to June 2022 were selected.The occurrence of delirium during ICU treatment were observed.The medical records of delirious and non delirious patients were compared.The binary logistic regression analysis were used to investigate the risk factors for early postoperative delirium.Results 28 out of 84 patients developed delirium.There were statistically significant differences between delirium and non delirium age,cardiopulmonary bypass time,ICU stay time,concomitant anxiety,sleep disorders,concomitant hypoxemia,use of benzodiazepines,and mechanical ventilation time(P<0.05).There was no significant difference in gender,disease type,diabetes and hypertension between the two groups(P>0.05).Binary logistic regression analysis showed that extracorporeal circulation time,ICU stay time,concomitant anxiety,sleep disorders,concomitant hypoxemia,and the use of benzodiazepines were risk factors for delirium.Conclusion Delirium is prone to occur in the early stage after cardiopulmonary bypass cardiac surgery,and prolonged cardiopulmonary bypass time and ICU stay can increase the risk of delirium.

关 键 词：体外循环 心脏手术 早期 谵妄 危险因素 

分 类 号：R749.2[医药卫生—神经病学与精神病学]