快速康复护理联合行为训练对结直肠癌患者的化疗效果以及不良情绪和认知功能的影响  

The effect of rapid rehabilitation nursing combined with behavioral training on chemotherapy for colorectal cancer and its impact on negative emotions and cognitive function in patients

作　　者：蒋成玲 胡云中[1] 马春梅 方先骏 JIANG Chengling;HU Yunzhong;MA Chunmei(Oncology DepartmentⅢ,Bozhou City People's Hospital of Anhui province,Bozhou236800,China)

机构地区：[1]安徽省亳州市人民医院肿瘤三科,亳州236800 [2]安徽医科大学

出　　处：《国际精神病学杂志》2024年第6期2005-2010,共6页Journal Of International Psychiatry

基　　金：安徽省自然科学基金项目(编号:1908085QH352)。

摘　　要：目的 研究快速康复护理联合认知行为训练对结直肠癌化疗患者的效果以及对其不良情绪和认知功能的影响。方法 选取2019年4月~2023年4月安徽省亳州市人民医院收治的98例结直肠癌化疗患者作为研究对象,并开展回顾性分析。根据管理方法不同将患者分为2组。观察组52例,行快速康复护理联合认知行为训练;对照组46例,行常规护理管理。比较两组化疗效果和不良反应发生情况。分别在干预前后采用汉密尔顿焦虑量表(hamilton anxiety scale,HAMA)和汉密尔顿抑郁量表(hamilton depression scale,HAMD)评估患者不良情绪,以简易智力状态检查量表(minimental state examination,MMSE)记录患者认知功能状态。结果 两组患者无进展生存率(PFS)和总生存率(OS)无统计学显著性差异(P>0.05),观察组化疗期间消化道反应、白细胞减少、血小板降低及贫血程度较对照组轻(P<0.05)。干预后观察组HAMD和HAMA评分低于对照组,MMSE评分高于对照组(P<0.05)。结论 快速康复护理联合认知行为训练用于结直肠癌术后化疗患者有助于减轻化疗不良反应,缓解负性情绪,改善认知功能。Objective To study the chemotherapy effect of rapid rehabilitation nursing combined with cognitive behavioral training for patients of colorectal cancer and its impact on negative emotions and cognitive function.Methods 98colorectal cancer chemotherapy patients admitted to Bozhou City People's Hospital of Anhui Province from April 2019 to April 2023 were selected as the research subjects and conducted retrospective analysis.The patients were divided into two groups,which based on different management methods.52 cases in the observation group received rapid rehabilitation nursing combined with cognitive behavioral training;46 cases in the control group received routine nursing management.The efficacy and incidence of adverse reactions between two groups of chemotherapy were compared.The Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD)were used to compare the negative emotions of patients before and after intervention,the cognitive function status of patients were recorded by the Mini Mental State Examination(MMSE).Results There were no significant difference in the progression free survival rate and overall survival rate between the two groups of patients(P>0.05).The observation group showed a significant reduction in gastrointestinal reactions,leukopenia,thrombocytopenia,and anemia during chemotherapy,which compared with the control group(P<0.05).After intervention,the HAMD and HAMA scores of the observation group were lower than those of the control group,and the MMSE scores were higher than those of the control group(P<0.05).Conclusion The combination of rapid rehabilitation nursing and cognitive behavioral training for postoperative chemotherapy patients with colorectal cancer can help alleviate chemotherapy adverse reactions,correct negative emotions,and improve cognitive function.

关 键 词：结直肠癌 快速康复护理 认知行为训练 不良情绪 认知功能 

分 类 号：R740.05[医药卫生—神经病学与精神病学]