基于多维度营养状况评估的食管癌患者营养不良危险因素分析  

Risk factor analysis of malnourished patients with esophageal cancer based on multidimensional assessment

作　　者：洪虹 戴丽君 仲巧玲 江静 Hong Hong;Dai Lijun;Zhong Qiaoling;Jiang Jing(Department of Oncology,Hai'an Hospital of Traditional Chinese Medicine,Nantong 226600,Jiangsu,China)

机构地区：[1]海安市中医院肿瘤科,江苏南通226600

出　　处：《肿瘤代谢与营养电子杂志》2024年第6期847-853,共7页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：江苏省南通市卫健委课题(MSZ2022075)。

摘　　要：目的探究基于多维度营养状况评估的食管癌患者营养不良的危险因素分析。方法选取2019年3月至2023年3月海安市中医院肿瘤科收治的食管癌患者106例临床资料开展回顾性分析,通过多维度营养状况评估[全球领导人营养不良倡议(GLIM)、欧洲肠外肠内营养学会2015年营养不良专家共识(ESPEN 2015)及患者主观整体评估(PG-SGA)]评估106例食管癌患者营养状况,通过二元Logistic回归分析营养不良的影响因素。结果GLIM评估患者存在21例营养不良、ESPEN2015评估患者存在18例营养不良,PG-SGA评估患者存在19例营养不良,多维度综合评估患者存在27例营养不良。二元Logistic回归分析显示,年龄(>60岁)、有合并症、有家族史、病理阶段(Ⅲ~Ⅳ期)、病程(≥12个月)、消化道症状(≥2条)、不良饮食行为、卡诺夫斯凯计分(KPS)(<70分)均是影响食管癌患者营养不良危险因素(P<0.05)。结论基于多维度营养状况评估食管癌患者营养状况具有较好临床价值,年龄(>60岁)、有合并症、有家族史、病理阶段(Ⅲ~Ⅳ期)、病程(≥12个月)、消化道症状(≥2条)、不良饮食行为、KPS(<70分)均是影响食管癌患者营养不良危险因素,临床需加强重视。Objective To explore the risk factors of malnutrition in patients with esophageal cancer based on multidimensional nutritional status assessment.Method Clinical data of 106 patients with esophageal cancer admitted to the Oncology Department of Hai'an Hospital of Traditional Chinese Medicine from March 2019 to March 2023 were retrospectively analyzed.Through the global leadership initiative on malnutrition,the Global Leadership Initiative on Malnutrition(GLIM),European Society for Clinical Nutrition and Metabolism 2015(ESPEN 2015)and patient-generated subjective global assessment(PG-SGA)were used to evaluate the nutritional status of 106 patients with esophageal cancer,and the influencing factors of malnutrition were analyzed by binary Logistic regression.Result There were 21 cases of malnutrition assessed by GLIM,18 cases of malnutrition assessed by ESPEN 2015,19 cases of malnutrition assessed by PG-SGA,and 27 cases of malnutrition assessed by multidimensional comprehensive assessment.Binary Logistic regression analysis showed that age(>60 years old),comorbidities,family history,pathological stage(Ⅱ-Ⅳ),course of disease(≥12 months),gastrointestinal symptoms(≥2 items),poor diet behavior,and Kanofsky performance score(KPS)(<70 points)were all risk factors for malnutrition in patients with esophageal cancer(P<0.05).Conclusion Evaluating the nutritional status of esophageal cancer patients based on multidimensional nutritional status has good clinical value,age(>60 years),comorbidities,family history,pathological stage(Ⅱ-Ⅳ),duration of the disease(>12 months),gastrointestinal symptoms(≥2),poor dietary behaviors,and KPS(<70)are risk factors for malnutrition in patients with esophageal cancer,which need to be emphasized more in the clinic.

关 键 词：食管癌 患者主观整体评估 全球领导人营养不良倡议 营养状况 多维度营养状况评估 营养不良 危险因素 预后 

分 类 号：R73[医药卫生—肿瘤]