CT和MRI在肿瘤恶液质评估中的应用及研究进展  

Application and research progress of CT and MRI in the assessment of cancer cachexia

作　　者：刘姗灵 王莹娟 王传林 周岚[1] Liu Shanling;Wang Yingjuan;Wang Chuanlin;Zhou Lan(Department of Clinical nutrition,the Third Affiliated Hospital of Kunming Medical University(Yunnan Cancer Hospital),Kunming 650100,Yunnan,China)

机构地区：[1]昆明医科大学第三附属医院(云南省肿瘤医院)临床营养科,云南昆明650100

出　　处：《肿瘤代谢与营养电子杂志》2024年第6期872-877,共6页Electronic Journal of Metabolism and Nutrition of Cancer

摘　　要：肿瘤恶液质作为恶性肿瘤的主要并发症之一,主要特征涵盖骨骼肌减少、脂肪萎缩、全身炎症反应以及其他因素引起的器官功能障碍代谢异常。CT和MRI能够定性、定量测量肌肉面积、肌肉密度和肌肉内脂肪含量,利用影像学检查手段,测定患者骨骼肌面积、骨骼肌指数、腰大肌横向和轴向厚度指数等指标,更为准确客观地评估骨骼肌减少等情况,从而判定肿瘤恶液质的发生发展阶段,针对具体分期制定营养治疗方案。本文综合阐述CT、MRI在肿瘤患者的营养状况评估及肿瘤恶液质诊断中的应用与研究进展,对于存在营养风险或早期恶液质的患者,积极开展营养治疗,以延缓肿瘤恶液质的发生和发展,并改善患者临床结局。Cancer cachexia is a kind of major complication of various malignant tumors and is characterized by skeletal muscle atrophy,adipose tissue degeneration,systemic inflammation,and various metabolic abnormalities contribute to functional impairment.CT and MRI are capable of qualitatively and quantitatively measuring muscle area,muscle density,and muscle fat content.Utilizing advanced imaging techniques,we assessed skeletal muscle area,skeletal muscle index,lateral and axial psoas major muscle thickness indices,along with other relevant parameters in patients.This comprehensive evaluation aims to provide a more precise and objective assessment of sarcopenia and related conditions,facilitating the identification of malignant fluid occurrence and progression stages,thereby enabling the formulation of tailored nutritional treatment plans for specific phases.In this paper,we review the application and research progress of CT and MRI in the assessment of nutritional status and diagnosis of cancer cachexia in patients with tumors,and actively carry out nutritional therapy in patients with nutritional risk or early stage of cancer cachexia to delay the development and improve the clinical outcome of patients.

关 键 词：肿瘤恶液质 肌肉减少症 营养状况 营养诊断 计算机断层成像 磁共振成像 

分 类 号：R73[医药卫生—肿瘤]