经自然腔道取标本手术治疗结直肠癌的效果分析  

Effect of Surgical Treatment of Colorectal Cancer by Natural Cavity Specimen Collection

作　　者：吴创 Wu Chuang(Department of Colorectal Surgery,Yulin Second People's Hospital,Yulin 537000,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]玉林市第二人民医院肛肠外科,广西壮族自治区玉林537000

出　　处：《中外医药研究》2025年第1期43-45,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析经自然腔道取标本(NOSES)手术治疗结直肠癌的效果。方法:选取2022年1月—2023年12月玉林市第二人民医院收治的结直肠癌患者60例为研究对象,采用随机数字表法分为对照组与观察组,每组30例。对照组行腹腔镜结直肠癌切除术,观察组行NOSES手术。比较两组术后康复时间、应激反应指标、疼痛程度、并发症发生情况。结果:观察组首次排气时间、首次下床活动时间、肠鸣音恢复时间、住院时间均短于对照组(P<0.001)。术前,两组丙二醛、超氧化物歧化酶水平比较,无统计学差异(P>0.05);术后,两组丙二醛水平高于术前,超氧化物歧化酶水平低于术前,观察组优于对照组(P<0.05)。术后1 d,观察组视觉模拟评分法(VAS)评分低于对照组(P<0.001);术后1周,两组VAS评分低于术后1 d,观察组低于对照组(P<0.05)。两组并发症总发生率比较,无统计学差异(P>0.05)。结论:NOSES手术治疗结直肠癌的效果显著,可加速术后康复,减轻应激反应,缓解疼痛,且未增加并发症发生风险。Objective:To analyze the effects of natural cavity specimen collection(NOSES)in surgical treatment of colorectal cancer.Methods:Sixty patients with colorectal cancer admitted to Yulin Second People's Hospital from January 2022 to December 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with thirty cases in each group.The control group underwent laparoscopic colorectal cancer resection and the observation group underwent NOSES surgery.The postoperative recovery time,stress response index,pain degree and complications were compared between the two groups.Results:The first exhaust time,the first time to get out of bed,the recovery time of bowel sound and the length of hospital stay in the observation group were shorter than those in the control group(P<0.001).Before surgery,there were no significant differences in the levels of malondialdehyde and superoxide dismutase between the two groups(P>0.05).After surgery,the level of malondialdehyde was higher than before surgery,the level of superoxide dismutase was lower than before surgery,and the observation group was better than the control group(P<0.05).On postoperative day 1,the visual analog scale(VAS)score of the observation group was lower than that of the control group(P<0.001).One week after surgery,VAS score of both groups was lower than that of the first day after surgery,and that of the observation group was lower than that of the control group(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion:NOSES has been shown to be effective in the treatment of colorectal cancer,accelerating postoperative recovery,reducing stress responses,and relieving pain without increasing the risk of complications.

关 键 词：结直肠癌 经自然腔道取标本手术 腹腔镜结直肠癌切除术 

分 类 号：R735.3[医药卫生—肿瘤]