妇科恶性肿瘤淋巴结清除术后乳糜瘘发生影响因素  

Influencing factors of the chylous fistula of patients with gynecological malignant tumor after lymph node dissection

作　　者：徐艳[1] 黄琴[1] 宋晓慧 XU Yan;HUANG Qin;SONG Xiaohui(Qingdao Hospital,University of Health and Rehabilitation Sciences(Qingdao Municipal Hospital),Qingdao,ShandongProvince,266000)

机构地区：[1]康复大学青岛医院,青岛市市立医院,266000

出　　处：《中国计划生育学杂志》2025年第1期199-202,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨妇科恶性肿瘤淋巴结清除术后发生乳糜瘘的影响因素。方法:收集2020年1月-2023年12月本院收治的妇科恶性肿瘤淋巴结清除术患者311例临床资料,根据术后乳糜瘘发生情况分为乳糜瘘组33例、对照组278例。收集分析患者临床资料,采用多因素logistic回归模型分析妇科恶性肿瘤淋巴结清除术后乳糜瘘发生的危险因素。结果:单因素分析结果显示,两组年龄、体质指数、甘油三酯水平、合并贫血、肿瘤类型、手术方式、术中出血量、腹主动脉旁淋巴结转移、FIGO分期、术后感染、术后化疗、术后出血、淋巴结肿大、术前白蛋白均无差异(均P>0.05)。多因素分析显示,低蛋白血症、淋巴结清扫水平为肾静脉、淋巴结清扫数目>33个均为妇科恶性肿瘤淋巴结清除术后乳糜瘘发生的危险因素(P<0.05)。结论:妇科恶性肿瘤淋巴结清除术后发生乳糜瘘为多种因素作用,提示临床重视相关危险因素,及时治疗,延缓疾病进展。Objective:To study the influencing factors of the chylous fistula of patients with gynecological malignant tumor after lymph node dissection.Methods:The clinical data of 31l patients with gynecologic malignant tumor treated in the hospital from January 2020 to December 2023 were selected in this study.According to the occurrence of chylous fistula after gynecologic malignant tumor lymph node dissection,33 patients with chylous fistula were included in study group and 278 patients without chylous fistula were included in control group.The clinical data of the patients in the two groups were collected and analyzed.The risk factors of the chylous fistula of the patients with gynecological malignant tumor after lymph node dissection were analyzed by multivariate logistic regression model.Results:Univariate analysis showed that there were no significant differences in the age,the body mass index,the triglyceride level,the anemia,the tumor type,the surgical method,the intraoperative blood loss,the para-aortic lymph node metastasis,the FIGO stage of the tumor,the postoperative infection,the postoperative chemotherapy,the postoperative bleeding,the lymph node enlargement and the preoperative albumin level of the patients between the two groups(all P>0.05).Multivariate analysis showed that the hypoproteinemia,the renal vein lymph node dissection,and the number of lymph node dissection>33 lymph nodes of the patients were the risk factors of their chylous fistula after the gynecological malignant tumor lymph node dissection(P<o.05).Conclusion:The chylous fistula occurrence of the patients after the gynecological malignant tumor lymph node dissection is influenced by many risk factors,so it is suggested that the related risk factors should be paid attention to in clinic and the timely treatment should be given in order to delay the progression of the disease.

关 键 词：妇科恶性肿瘤 淋巴结清除术 乳糜瘘 影响因素 

分 类 号：R73[医药卫生—肿瘤]