Estimated inorganic arsenic from total arsenic in fishery products and its health risk to the Indonesian population  

作　　者：Dwiyitno Dwiyitno Nuri Andarwulan Hanifah Nuryani Lioe Nelis Imanningsih Puspo Edi Giriwono Deksa Presiana Rina Adriany Eva Nikastri Novi Pusparini Ilaine Audia Ninda Nur Amaliya Famila Takhwifa 

机构地区：[1]Research Center for Food Technology and Processing,BRIN,Jl.Jogja-Wonosari KM 31.5,Gunungkidul,55681,Indonesia [2]Department of Food Science and Technology,IPB University,PO Box 220,Bogor,16110,Indonesia [3]Southeast Asia Food and Agricultural Science and Technology(SEAFAST)Center,IPB University,Jl.Puspa No.1,Kampus IPB Darmaga,Bogor,16680,Indonesia [4]Health Policy Agency,Ministry of Health Republic of Indonesia,Jl.Percetakan Negara No.29,Jakarta,10560,Indonesia [5]National Agency of Drug and Food Control Republic of Indonesia,Jl.Percetakan Negara No.23,Jakarta,10560,Indonesia

出　　处：《Emerging Contaminants》2024年第4期92-102,共11页新兴污染物(英文)

摘　　要：The present study is the first assessment of inorganic arsenic exposure from various fishery products to the Indonesian population based on a national total diet study(TDS).Based on the TDS report on food chemical contaminants,fish and processed fishery products are among the foodstuffs significantly contributing to total arsenic(t-As)exposure in Indonesia.However,there is no assessment yet for the Indonesian population to inorganic arsenic(i-As),which is known as the most harmful of arsenic compounds as it potentially promotes acute and chronic poisoning.The present assessment is aimed to estimate the exposure to i-As from fish and processed fishery products as well as the level of health risks in different age groups in Indonesia,based on the available t-As concentration data.The results showed that the mean exposure to t-As and i-As from fish and processed fishery products in various age groups were 1.19-2.67 μg/kg bw/day and 0.04-0.08 mg/kg bw/day,respectively.Exposure in various age groups revealed that the highest arsenic exposure was in toddlers(0-4 years)and the lowest in the age group of 19-55 years.Wet seasonings and marine fish consumption led to the most contributors to i-As exposure.The carcinogenic risk of i-As exposure based on the margin of exposure(MOE)demonstrated a low to moderate risk.However,a particular concern to the toddler group is required as the cancer risk(CR)value is higher than the acceptable threshold(>10^(-4)).Additionally,the hazard quotient(HQ)of i-As exposure was determined as a low possibility of chronic risk.

关 键 词：Inorganic arsenic Total arsenic Fishery products EXPOSURE Health risk 

分 类 号：R73[医药卫生—肿瘤]