羟基氧化钴纳米片的飞秒激光液相烧蚀及其抗氧化剂检测应用研究  

Fabrication of CoOOH nanosheet by femtosecond laser liquid phase ablation and its application in antioxidant detection

作　　者：袁艳萍[1,2] 王文博 郭筱然 YUAN Yan-ping;WANG Wen-bo;GUO Xiao-ran(Institute of Laser Engineering,Department of Materials and Manufacturing,Beijing University of Technology,Beijing 100124,China;Trans-scale Laser Manufacturing Technology Key Laboratory of Ministry of Education,Beijing 100124,China)

机构地区：[1]北京工业大学材料与制造学部激光工程研究院,北京100124 [2]跨尺度激光成型制造技术教育部重点实验室,北京100124

出　　处：《现代化工》2025年第2期79-83,共5页Modern Chemical Industry

基　　金：国家自然科学基金(52175374,51805014,51905531)。

摘　　要：纳米酶具有比传统酶更高、更广泛的底物适应性以及更好的稳定性,使其成为一种替代传统酶的生物催化剂。然而纳米酶通常需要在高温、高压甚至有毒条件下制备,工序复杂、耗时且能量效率不高。羟基氧化钴纳米片是一种典型的纳米材料,具有出色的氧化酶相似活性。在常温、常压且无需添加任何化学试剂稳定的条件下,利用飞秒激光液相烧蚀技术成功制备了晶面规则完整的羟基氧化钴纳米片,其与四甲基联苯胺在显色反应中更易结合且反应效率更高。通过显色反应检测了多种抗氧化物质,结果表明,该方法成本低、操作简单、灵敏度高、易观察,在生物化学检测和食品安全检测等领域具有极大的应用潜能。Traditional enzymes are often used in biological detection,but nano-enzymes has higher and wider substrate adaptability and better stability than traditional enzymes.These advantages make nano-enzymes become a biocatalyst to replace traditional enzymes.However,nano-enzymes usually need to be prepared under high temperature and pressure,or even toxic conditions,and the process is complicated,long-time required,and inefficient.Hydroxyl cobalt oxide(CoOOH)nanosheet is a typical nanomaterial with excellent oxidase-like activity.In this study,CoOOH nanosheets with regular and complete crystal surface is successfully prepared through femtosecond laser liquid phase ablation technology at room temperature and normal pressure without adding any chemical reagents.The prepared CoOOH nanosheets are easier to bind with tetramethylbenzidine in the color reaction and present higher reaction efficiency.Various antioxidant substances are detected by the prepared CoOOH nanosheets through color reaction.It is verified that this method has advantages of low cost,simple operation,high sensitivity,and easy observation,showing a great application potential in the fields of biochemical detection and food safety detection.

关 键 词：羟基氧化钴纳米片 飞秒激光 液相烧蚀 抗氧化物质 纳米酶 液相 

分 类 号：O657.31[理学—分析化学] X832[理学—化学]