In situ imaging of microplastics in living organisms based on mass spectrometry technology  

作　　者：Ye Li Xiaoyu Sha Yuan Wang Yanfang Zhao Junje Zhang Ping Wang Xiangfeng Chen Baoshan Xing Lei Wang 

机构地区：[1]Stockbridge School of Agriculure,University of Massachusetts,Amherst,MA,USA [2]MOE Key Laboratory of Pllution Processes and Environmentai Crteria,College of Environmertal Science and Engineering,Nankai University,Tianjin 300071,China [3]School of Pharmaceutical Sciences,Qilu University of Technology(Shandong Acadery of Sciences),Jinan 250014,China [4]Analyical Chemistry Group,Department of Plant and Environmental Science,Faculty of Science,University of Copenhagen,1871 Predriksberg C,Denmark [5]School of Business,Qingdao University,Qingdao 266100,China

出　　处：《Eco-Environment & Health》2024年第4期412-417,共6页生态环境与健康(英文)

基　　金：funded by the National Natural Science Foundation of China (42077336);the Asia-Pacific Network for Global Change Research (CRRP2019-FP06-WANG);the 111 Program of the Ministry of Education of China (T2017002);Tianjin Research Innovation Project for Postgraduate Students (2021YJSB042).

摘　　要：Plastic pollution is widely present in terrestrial and aquatic ecosystems,and microplastics(MPs)can be detected in organisms.In situ detection methods for MPs in organisms have attracted widespread attention.Traditional imaging characterization methods of MPs,including stereo microscopes and fluorescence microscopy,are typically used to image artificially added microsphere standards under laboratory conditions.However,they cannot specifically identify MPs in biological samples.Thus,there is a need for a detection technique that can provide spatial distribution information of MPs in biological samples as well as measure their quality and quantity.In this perspective,to obtain high-resolution images with chemical composition analysis,we compared ion sources for ionizing plastic macromolecules and mass analyzers for analyzing macromolecules.Matrix-assisted laser desorption/ionization(MALDI)is suitable for imaging characterization,while time-of-flight(TOF)and Orbitrap mass spectrometry are suitable for polymer mass spectrometry analysis.Furthermore,we propose a technique that combines MALDI with TOF or Orbitrap,which holds promise for the in situ imaging of MPs in biological samples.

关 键 词：Microplastics ORGANISMS In situ imaging Mass spectrometry imaging 

分 类 号：F42[经济管理—产业经济]