氧化应激对雄激素性脱发的发病机制及其研究进展  

The Pathogenesis and Research Progress of Oxidative Stress on Androgenic Alopecia

作　　者：马晓敏 梁丹妮 张凯云 张嘉(综述) 张国惠(审校) MA Xiaomin;LIANG Danni;ZHANG Kaiyun;ZHANG Jia;ZHANG Guohui(Baotou Clinical Medical College Inner Mongolia Medical University,Baotou 014040,Inner Mongolia,China;Department of Dermatology,Baotou Central Hospital,Baotou 014040,Inner Mongolia,China;Inner Mongolia University of Science and Technology Baotou Medical College,Baotou 014040,Inner Mongolia,China)

机构地区：[1]内蒙古医科大学包头临床医学院,内蒙古包头014040 [2]包头市中心医院皮肤科,内蒙古包头014040 [3]内蒙古科技大学包头医学院,内蒙古包头014040

出　　处：《中国美容医学》2025年第2期189-192,共4页Chinese Journal of Aesthetic Medicine

基　　金：包头市社会发展科技支撑项目(编号:2017S2001-4-7)。

摘　　要：雄激素性脱发(Androgenetic alopecia,AGA)作为最常见的脱发类型,表现为头发密度进行性减少,是一种依赖雄激素且遗传的多发性疾病,往往对患者的外貌和心理以及职业选择产生严重影响。因此,近年来国内外有关雄激素性脱发的发病机制及其治疗研究成为热点,该综述就AGA发病机制中氧化应激的相关性进行阐述,为AGA的精准治疗奠定科学依据。As the most common type of hair loss,androgenetic alopecia is characterized by progressive loss of hair density.It is an androgen-dependent and genetic multiple disease,which often has a serious impact on the patient's appearance and psychology,as well as career choices.Therefore,research on the pathogenesis and treatment of androgenetic alopecia at home and abroad has become a hot spot in recent years.This review will explain the correlation of oxidative stress in the pathogenesis of AGA,laying a scientific basis for the precise treatment of AGA.

关 键 词：雄激素性脱发 氧化应激 WNT/Β-CATENIN信号通路 TGF-Β信号通路 

分 类 号：R73[医药卫生—肿瘤]