麦默通微创旋切术与常规乳腺肿物切除术治疗乳腺良性肿块的疗效分析  

Efficacy Analysis of Mammotome Minimally Invasive Vacuum-Assisted Excision vs.Conventional Breast Tumor Excision in the Treatment of Benign Breast Masses

作　　者：汪邦辉 邱丽贞 WANG Banghui;Qiu Lizhen(Pucheng County HospitalGeneral Surgery Department,Pucheng 353400,China;Fuzhou University Affiliated Provincial HospitalThyroid Hernia Surgery,Fuzhou 350001,China)

机构地区：[1]浦城县医院普外科,福建浦城353400 [2]福州大学附属省立医院甲状腺疝外科,福建福州350001

出　　处：《中华灾害救援医学》2024年第12期1436-1439,共4页Chinese Journal of Disaster Medicine

摘　　要：目的分析麦默通微创旋切术和常规肿物切除术治疗乳腺良性肿块的临床疗效。方法选择2024年1月至2024年10月来浦城县医院就诊的60例行手术治疗的乳腺良性肿块患者,根据随机数字表分组法,分为麦默通微创旋切术组(观察组)和常规乳腺肿物切除术组(对照组),每组30例。比较两组患者的手术相关指标、术后乳房美观效果、血管内皮生长因子、催乳素、微血管密度、术后并发症发生情况。结果与对照组相比,观察组手术时间、切口愈合时间、住院时间明显更短,且术中出血量更少,切口长度更短,差异均具有统计学意义(P<0.001)。观察组患者乳房形态、乳头敏感程度、切口瘢痕、色素沉着评分均更高(P<0.001)。观察组术后并发症的发生率较低(P<0.05)。两组患者术后组内比较,血管内皮生长因子水平均降低(P<0.05),催乳素水平均升高(P<0.05),微血管密度无明显改变(P>0.05);且和对照组相比,观察组内皮生长因子和催乳素水平更低(P<0.001),两组微血管密度组间比较无显著差异(P>0.05)。结论对于乳腺良性肿块患者,麦默通乳腺旋切术可缩短手术、创口愈合、住院时间,减少术中出血量,减少对乳房美观的影响,降低血管内皮生长因子和催乳素水平,而对微血管密度无明显影响,且安全性高。Objective To analyze the clinical efficacy of the Maimetong minimally invasive rotational excision technique compared to conventional tumor excision for benign breast lesions.Methods A total of 60 patients diagnosed with benign breast tumors who underwent surgical treatment at Pucheng County Hospital from January to October 2024 were selected.Based on a random number table method,patients were divided into two groups:the Maimetong minimally invasive rotational excision group(observation group)and the conventional tumor excision group(control group),with 30 patients in each group.Surgical-related indicators,postoperative cosmetic outcomes,levels of vascular endothelial growth factor(VEGF),prolactin,microvascular density,and the incidence of postoperative complications were compared between the two groups.Results Compared to the control group,patients in the observation group experienced significantly shorter surgical times,wound healing times,and hospital stays,along with reduced intraoperative blood loss and shorter incision lengths,with statistically significant differences(P<0.001).The observation group also had higher scores for cosmetic outcomes related to breast shape,nipple sensitivity,incision scars,and pigmentation(P<0.001).The incidence of postoperative complications in the observation group was lower(P<0.05).Within each group,postoperative comparisons showed a decrease in VEGF levels and an increase in prolactin levels,with no significant changes in microvascular density.Additionally,the observation group had lower VEGF and prolactin levels compared to the control group(P<0.001),while there were no significant intergroup differences in microvascular density.Conclusion For patients with benign breast tumors,the Maimetong minimally invasive rotational excision technique can significantly reduce surgical duration,wound healing time,and hospital stay,decrease intraoperative blood loss,minimize the impact on breast aesthetics,and lower levels of vascular endothelial growth factor and prolactin,without signif

关 键 词：乳腺良性肿块 麦默通微创旋切术 血管内皮生长因子 

分 类 号：R737.9[医药卫生—肿瘤]