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作 者:Mehmet C.Yildirim Hatice S.Ekici Jemima Collins Jessica Piasecki Rob Skelly Adam L.Gordon Bethan E.Phillips
机构地区:[1]Academic Unit of Injury,Recovery and Inflammation Sciences(IRIS),School of Medicine,University of Nottingham,Derby,UK [2]Department of Medicine of the Elderly,University Hospitals of Derby and Burton NHS Foundation Trust,Royal Derby Hospital,Derby,UK [3]Musculoskeletal Physiology Research Group,Sport,Health and Performance Enhancement Research Centre,School of Science and Technology,Nottingham Trent University,Nottingham,UK
出 处:《Translational Exercise Biomedicine》2024年第3期195-211,共17页运动转化生物医学(英文)
基 金:Mehmet Cagatay Yildirim is funded through the YLSY scholarship programme provided by the Ministry of National Education of the Republic of Turkiye.Adam Gordonisan NIHR Senior Investigator and part-funded through the NIHR Applied Research Collaboration-East Midlands(ARC-EM).This work was supported by the Medical Research Council(MRC)-Versus Arthritis Centre for Musculoskeletal Ageing Research(CMAR)via agrant from the MRC[MR/P021220/1],the MRC[MR/X005240/1],and the Nottingham NIHR Biomedical Research Centre.
摘 要:Introduction Parkinson’s disease(PD)is a neurodegenerative disorder with increasing prevalence into older age.Aerobic exercise(AE)is the most commonly prescribed exercise for PD,although an optimal protocol is undefined.This umbrella review aimed to summarise and synthesize existent evidence regarding the effectiveness of AE on balance,gait,functional mobility,and QoL in people with PD.Content Six databases were searched for systematic reviews reporting the effects of AE on balance,gait,functional mobility,and QoL in people with PD from inception to June 2024.Quality of evidence was assessed using the AMSTAR-2 tool.From 4182 records,17 systematic reviews were included for qualitative analysis.Most(n=12)were rated as critically low for methodological quality,with four rated low and one high.Moderate intensity was the most commonly investigated AE intensity(n=4),although almost half of the reviews(n=8)did not report intensity.AE protocols lasted from 1 to 64 weeks and 1 to 7 days per week.Session length was between 20 and 120 minutes.Reported outcomes included gait(n=15),QoL(n=14),balance(n=12),and functional mobility(n=7).AE does improve aspects of gait,balance,and functional mobility in PD;however it does not appear to improve QoL.Summary and Outlook AE is recommended as part of rehabilitation for people with PD.However,research exploring the efficacy of AE assesses multiple modalities with varied protocols.Further research is needed to identify AE protocols that will best alleviate the symptoms of PD,providing an evidence base for effective clinical translation.
关 键 词:Parkinson’s disease aerobic exercise quality of life older people umbrella review balance
分 类 号:R74[医药卫生—神经病学与精神病学]
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