多系统萎缩异常眼球运动的研究进展  

Research advances in abnormal eye movements in multiple system atrophy

作　　者：赵丽娟(综述)[1,2] 钱淑霞(审校) ZHAO Lijuan;QIAN Shuxia(Jiaxing University Master Degree Cultivation Base,Zhejiang Chinese Medical University,Hangzhou 310053,China)

机构地区：[1]浙江中医药大学嘉兴大学联培基地,浙江杭州310053 [2]浙江省嘉兴大学附属第二医院神经内科,浙江嘉兴314000

出　　处：《中风与神经疾病杂志》2025年第1期30-33,共4页Journal of Apoplexy and Nervous Diseases

摘　　要：多系统萎缩(MSA)是一种罕见的神经系统变性疾病,临床表现多样且不典型,与α-突触核蛋白谱系病中的其他疾病存在重叠现象。疾病的诊断及早期鉴别诊断方面临巨大的挑战,漏诊、误诊的情况时有发生,从而延误疾病的治疗。眼震视图(VNG)是目前评估前庭功能的主要无创检查,可提供不同的眼动参数。有研究表明,多系统萎缩患者中存在异常的眼球运动。本文从视觉-眼动的角度,综述其对多系统萎缩患者的研究现状,尽可能揭示其内在联系,为MSA的早期诊断提供参考。Multiple system atrophy(MSA)is a rare degenerative disease of the nervous system and has diverse and atypical clinical manifestations,and it overlaps with other diseases inα-synuclein spectrum disease.There are great challenges in the diagnosis and early differential diagnosis of the disease,and missed diagnosis and misdiagnosis occur from time to time,thereby delaying the treatment of the disease.Videonystagmography(VNG)is currently the main noninvasive test used to assess vestibular function and can provide different eye movement parameters.Studies have shown the presence of abnormal eye movements in patients with MSA.From the perspective of vision-eye movement,this article reviews the current status of research on eye movements in patients with MSA and reveals the internal connection between them,in order to provide an important reference for the early diagnosis of MSA.

关 键 词：多系统萎缩 视频眼震图 凝视 扫视 平稳追踪 视动性眼球震颤 

分 类 号：R742[医药卫生—神经病学与精神病学]