黑龙江省农村地区癫痫治疗现状以及苯巴比妥疗效分析  

Current status of epilepsy treatment and efficacy of phenobarbital in rural areas of Heilongjiang Province,China

作　　者：何伟丽[1] 安娜 周勇 秦爱萍[1] 和一展 闫世春[1] HE Weili;AN Na;ZHOU Yong(Division of Chronic Disease Control and Prevention,Heilongjiang Provin-cial Center for Disease Control and Prevention,Harbin 150030,China)

机构地区：[1]黑龙江省疾病预防控制中心慢性非传染性疾病预防与控制所,黑龙江哈尔滨150030

出　　处：《中风与神经疾病杂志》2025年第1期52-55,共4页Journal of Apoplexy and Nervous Diseases

基　　金：中央补助地方农村地区癫痫防治管理项目(2021104)。

摘　　要：目的 掌握黑龙江省农村地区惊厥性癫痫患者治疗现状,分析苯巴比妥治疗癫痫的效果,评价农村癫痫防治管理项目实施的成效。方法 运用EpiData、EXCEL和SPSS 19.0软件进行数据录入、处理和统计描述,对黑龙江省农村癫痫治疗现状和苯巴比妥剂量、癫痫发作频率进行分析。收集2015—2020年黑龙江省癫痫防治管理项目纳入苯巴比妥管理组治疗组中的908例惊厥性癫痫患者,经规范化治疗及随访管理,满12个月患者共698例。结果 黑龙江省农村癫痫治疗缺口率为56.39%;经过1年规范治疗,癫痫发作频率由入组管理前的23.86次/年下降为3.11次/年,发作频率显著降低,癫痫治疗有效率为68.19%,相比经正规治疗的患者,既往未经过正规治疗的患者效果更好。结论 黑龙江省农村地区癫痫治疗现状不容乐观,还存在很大缺口,应加强对基层医生癫痫诊断治疗知识的培训,并大力开展癫痫防治知识宣传教育。苯巴比妥治疗癫痫效果显著,建议在农村地区推广使用。Objective To investigate the current status of treatment for patients with convulsive epilepsy in ru-ral areas of Heilongjiang Province,China and the efficacy of phenobarbital in the treatment of epilepsy,and to evalu-ate the effect of the epilepsy prevention and management project in rural areas.Methods EpiData,EXCEL,and SPSS 19.0 were used for data entry,processing,and statistical description to analyze the current status of epilepsy treatment in rural areas,the dose of phenobarbital,and the frequency of seizures.In the epilepsy prevention and management project of Heilongjiang Province in 2015—2020,a total of 908 patients with convulsive epilepsy were en-rolled in the phenobarbital treatment group,and after standardized treatment and follow-up management,698 pa-tients were followed up for at least 12 months.Results The gap rate of rural epilepsy treatment in Heilongjiang Prov-ince was 56.39%.After one year of standardized treatment,the frequency of seizures decreased from 23.86 times/year before enrollment to 3.11 times/year,showing a significant reduction.The response rate of epilepsy treatment was 68.19%,and the patients without previous standard treatment tended to have a better outcome than those who re-ceived standard treatment.Conclusion The current status of epilepsy treatment is not optimistic in rural areas of Heilongjiang Province,and there remains a large gap in epilepsy treatment.It is necessary to strengthen the training on the diagnosis and treatment of epilepsy among primary care physicians and implement the public education on the prevention and treatment of epilepsy,and since phenobarbital has a marked clinical effect in the treatment of epi-lepsy,it holds promise for further application in rural areas.

关 键 词：农村地区 癫痫 治疗现状 苯巴比妥 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R741.05[医药卫生—临床医学]