C反应蛋白与白蛋白比值联合NRS2002评分对高血压脑出血患者短期预后的预测价值  

Predictive value of C-reactive protein to albumin ratio combined with NRS2002 score for short-term prognosis in patients with hypertensive intracerebral hemorrhage

作　　者：李蒙[1] 付三仙[1] 王素凡 周力为[1] 梁锐[1] 吕全军 LI Meng;FU Sanxian;WANG Sufan;ZHOU Liwei;LIANG Rui;LYU Quanjun(Department of Clinical Nutrition,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052;Henan Key Laboratory of Chronic Disease Prevention and Therapy&Intelligent Health Management,Zhengzhou 450052)

机构地区：[1]郑州大学第一附属医院临床营养科,郑州450052 [2]河南省慢病防治与智慧健康管理重点实验室,郑州450052

出　　处：《郑州大学学报(医学版)》2025年第1期106-109,共4页Journal of Zhengzhou University(Medical Sciences)

基　　金：国家自然科学基金项目(82103817);河南省中原医学科技创新发展基金会项目(23YCG1015)。

摘　　要：目的:探讨C反应蛋白与白蛋白比值(CAR)联合营养风险筛查常用量表评分(NRS2002评分)对高血压脑出血患者短期预后的预测价值。方法:选取2023年1至10月郑州大学第一附属医院收治的294例高血压脑出血患者为研究对象,根据发病90 d内的生存情况分为生存组(n=223)和死亡组(n=71)。采用Logistic回归分析筛选高血压脑出血患者短期预后的危险因素,通过ROC曲线下面积(AUC)评价CAR、NRS2002评分及CAR联合NRS2002评分对高血压脑出血患者短期预后的预测效能。结果:Logistic回归分析显示,CAR和NRS2002评分是高血压脑出血患者预后的危险因素[OR(95%CI)分别为1.212(1.026~1.432)、1.510(1.233~1.849),P<0.05]。CAR联合NRS2002评分预测高血压脑出血患者短期预后的方程为Y=-3.242+0.412×NRS2002+0.192×CAR,预测短期预后的AUC(95%CI)为0.711(0.639~0.782),敏感度和特异度分别为0.648、0.709。结论:CAR联合NRS2002评分预测高血压脑出血患者短期预后具有一定的价值。Aim:To investigate the predictive value of C-reactive protein to albumin ratio(CAR)combined with the Nutritional Risk Screening 2002(NRS2002)score for the short-term prognosis of patients with hypertensive intracerebral hemorrhage.Methods:A total of 294 patients with hypertensive intracerebral hemorrhage admitted to the First Affiliated Hospital of Zhengzhou University from January to October 2023 were selected,and allocated into survival group(n=223)and death group(n=71)according to the survival status 90 days after onset.Logistic regression analysis was used to screen the risk factors for short-term prognosis of patients with hypertensive intracerebral hemorrhage,and the predictive efficacy of CAR,NRS2002 score and CAR+NRS2002 score on the short-term prognosis was evaluated by ROC.Results:Logistic regression analysis showed that CAR and NRS2002 score were risk factors for short-term prognosis of patients with hypertensive intracerebral hemorrhage[OR(95%CI)was 1.212(1.026-1.432)and 1.510(1.233-1.849),respectively,P<0.05].The equation for predicting short-term prognosis by CAR+NRS2002 score was Y=-3.242+0.412×NRS2002+0.192×CAR,and AUC(95%CI)of CAR+NRS2002 score for predicting short-term prognosis was 0.711(0.639-0.782),with sensitivity and specificity of 0.648 and 0.709,respectively.Conclusion:CAR+NRS2002 score has a certain value in predicting short-term prognosis in patients with hypertensive intracerebral hemorrhage.

关 键 词：C反应蛋白与白蛋白比值 NRS2002评分 高血压脑出血 短期预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]