Change in EEG-EMG synchronization reflecting abnormal functional corticomuscular coupling following stroke: A pilot study  

作　　者：Xiaoling Chen Jinyuan Zhang Yingying Hao Ying Liu Yinan Yang Ping Xie 

机构地区：[1]Key Laboratory of Measurement Technology and Instrumentation of Hebei Province,Institute of Electric Engineering,Yanshan University,Qinhuangdao,Hebei,China [2]Key Laboratory of Intelligent Rehabilitation and Neuromodulation of Hebei Province,Institute of Electric Engineering,Yanshan University,Qinhuangdao,Hebei,China [3]Department of Rehabilitation Medicine,First Hospital of Qinhuangdao,Qinhuangdao,Hebei,China

出　　处：《Medicine in Novel Technology and Devices》2024年第4期102-110,共9页医学中新技术与新装备(英文)

基　　金：This work was funded by the National Natural Science Foundation of China under grant(No.U20A20192and No.62076216);Natural Science Foundation of Hebei Province of China grant(No.F2022203079and No.F2022203002);the Key Research and Development Program of Hebei Province of China(No.21372005D);the Funding Program for Innovative Ability Training of graduate students of Hebei Provincial Department of Education grant(No.CXZZSS2022123).

摘　　要：Stroke is a common clinical cardiovascular and cerebrovascular disease,which can cause severe motor dysfunction.Therefore,it is an important topic to investigate the abnormality mechanism of the cerebral cortex and the corresponding muscles after stroke.In this study,we investigated the functional corticomuscular coupling(FCMC)at specific frequencies by analyzing differences between stroke patients and healthy controls in hand movements.The transfer spectral entropy(TSE)method was used to analyze simultaneous electroencephalography(EEG)and electromyography(EMG)in the right-hand steady state force task.The results illustrated that healthy subjects had the highest TSE values at the beta band in the EMG→EEG and EEG→EMG directions,and the TSE value in the EEG→EMG direction was higher than that in the EMG→EEG direction.In contrast,for stroke patients,beta band coupling was weakened,and there was a notably higher enhancement of alpha and gamma bands in the EMG→EEG direction relative to the EEG→EMG direction.Further analysis found significant correlations between TSE area values at beta2 and gamma2 bands and clinical rating scales.This study demonstrates the frequency specificity properties of FCMC estimated by TSE can assess the rehabilitation status of stroke patients and contribute to our comprehension of the potential mechanism of motor control systems.

关 键 词：Functional corticomuscular coupling Frequency-specific characteristics Transfer spectral entropy STROKE 

分 类 号：R74[医药卫生—神经病学与精神病学]