Targeting novel sites represents an effective strategy for combating drug resistance  

作　　者：Shaoqing Du Xinyong Liu Xueping Hu Peng Zhan 

机构地区：[1]Department of Medicinal Chemistry,Key Laboratory of Chemical Biology(Ministry of Education),School of Pharmaceutical Sciences,Cheeloo College of Medicine,Shandong University,Ji’nan 250012,China [2]Institute of Frontier Chemistry,School of Chemistry and Chemical Engineering,Shandong University,Qingdao 266237,China

出　　处：《Chinese Chemical Letters》2025年第1期3-5,共3页中国化学快报(英文版)

摘　　要：Drug resistance poses an escalating global challenge in the battle against infections.The effectiveness of conventional antibiotics and other anti-infective drugs is waning as microbes develop heightened resistance to existing treatments.Antimicrobial resistance poses a formidable challenge to global health and development,ranking among the top 10 public health threats to humanity as declared by the World Health Organization.Projections indicate that if left unaddressed,antimicrobial resistance could inflict an annual economic burden on the global GDP ranging from$1trillion to$3.4 trillion by 2030.Consequently,the management of common infections becomes increasingly arduous,while the likelihood of disease transmission,severe illness,and mortality escalates.

关 键 词：resistance DRUGS HUMANITY 

分 类 号：R96[医药卫生—药理学]