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作 者:Wei Sun Anjing Liao Li Lei Xu Tang Ya Wang Jian Wu
出 处:《Chinese Chemical Letters》2025年第1期58-67,共10页中国化学快报(英文版)
基 金:financial support from the National Natural Science Foundation of China(No.32072445);the Science and Technology Plan Project of Guizhou Province(Qiankehezhicheng[2024]the general 083);the Program of Introducing Talents to Chinese Universities(No.D20023);the Central Government Guides Local Science and Technology Development Fund Projects(Qiankehezhongyindi(2023)001);the Technology Achievement Transformation(general project)of Guizhou Province(Qiankehechengguo[2022]the general 063);Key Agricultural Technology R&D Projects of the Xinjiang Production and Construction Corps(NYHXGG,No.2023AA602);the Frontiers Science Centre for Asymmetric Synthesis and Medicinal Molecules;Department of Education;Guizhou Province[Qianjiaohe KY(2020)004];the specific research fund of TheInnovation Platform for Academicians of Hainan Province(No.SQ2020PTZ0009)。
摘 要:Piperidine is a crucial pharmacophore and a special scaffold in the realm of drug discovery.Its flexibility increases the molecule’s capability to bind to the receptor.The piperidine-containing compounds are distinguished by their remarkable activity,and are increasingly becoming a vital category of pesticides.In this review,the research progress of piperidines in the discovery of pesticides was updated according to their active characteristics.The structure-activity relationships(SARs),and mechanisms of action of piperidine-containing compounds were also discussed.This article is meant to enable readers to quickly understand piperidines,while providing ideas for creating piperidines with novel structures and unique mechanisms of action.
关 键 词:PIPERIDINE Agrochemicals Biological activity Structure-activity relationships Mechanism of action
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